9-Methyl-9H-beta-carboline CAS No.:2521-07-5 99% maʻemaʻe min. no ka mea hoʻohui
Nā Palena Huahana
| Inoa huahana | 9-Me-BC |
| Inoa ʻē aʻe | 9-Methyl-9H-beta-carboline9-methyl-9h-pyrido[3,4-b]indole 9H-Pyrido[3,4-b]indole, 9-methyl- 9-Methyl-9H-pyrido(3,4-b)indole 9-methylpyrido[3,4-b]indole 9-methyl-beta-carboline 9-methylnorharman 9-methyl-9h-beta-carboline 9H-Pyrido(3,4-b)indole, 9-methyl- 9-Methylnorharmane |
| Helu CAS. | 2521-07-5 |
| ʻO ke ʻano molekole | C12H10N2 |
| Kaumaha molekole | 182.22 |
| Maʻemaʻe | 99% |
| helehelena | Melemele paʻa |
| Hoʻopili ʻana | 1kg/ʻEke; 25kg/Pahu Kāleka |
| Noi | Nā Mea Hoʻohui Meaʻai |
Hoʻolauna huahana
ʻO 9-Methyl-β-carboline (9-Me-BC) kahi amine heterocyclic o ka ʻohana β-carboline a he kemika noiʻi synthetic. He methylated derivative ia o β-carboline. ʻO ke ʻano kemika o 9-Me-BC he β-carboline core a me kahi hui methyl i hoʻopili ʻia i ke kūlana 9 o ka pyridinium [3,4-b] indole ring system. ʻAʻole ʻike ʻia he mau kumu kūlohelohe i ʻike ʻia ʻo 9-Me-BC. Hoʻonui ka 9-Me-BC i ka ʻike ma o nā ʻano hana he nui. Hoʻonui ia i ka tyrosine hydroxylase, ka enzyme e kaupalena ana i ka wikiwiki i ka synthesis dopamine, e alakaʻi ana i ka hoʻonui ʻana i nā pae dopamine. Hoʻopaʻa pū ka 9-Me-BC i ka hana monoamine oxidase (MAO), e pale ana i ka haki ʻana o ka dopamine a me nā neurotransmitters monoamine ʻē aʻe. Eia kekahi, hoʻoulu ka 9-Me-BC i nā astrocytes e hōʻike i nā mea neurotrophic, e paipai ana i ka ulu ʻana o ka neuronal a me ke ola. I nā kānaka olakino, hiki i ka 9-Me-BC ke hoʻomaikaʻi i ka ʻike ma ka hoʻomaikaʻi ʻana i nā pae neurotransmitter a me ke kākoʻo ʻana i ka ulu ʻana o ka neuronal. Hiki paha i kēia ke hoʻomaikaʻi i ka hoʻomanaʻo, ka nānā ʻana, a me ke aʻo ʻana. ʻO ka hiki o ka hui ke hoʻonui i nā pae BDNF a me NGF hiki ke kōkua i ke olakino noʻonoʻo lōʻihi, e lilo ana ʻo 9-Me-BC i koho kaulana no ka poʻe e ʻimi nei e hoʻomaikaʻi i ka hana noʻonoʻo a pale i ka emi ʻana o ka noʻonoʻo.
Hiʻona
(1) Maʻemaʻe kiʻekiʻe: Hiki i ka 9-Methyl-9H-beta-carboline ke loaʻa nā huahana maʻemaʻe kiʻekiʻe ma o nā kaʻina hana hana i hoʻomaʻemaʻe ʻia. ʻO ke ʻano o ka maʻemaʻe kiʻekiʻe ʻo ia hoʻi ka bioavailability maikaʻi aʻe.
(2) Paʻa: Loaʻa i ka 9-Methyl-9H-beta-carboline ke kūpaʻa maikaʻi a hiki ke mālama i kāna hana a me ka hopena ma lalo o nā ʻano like ʻole a me nā kūlana mālama.
(3) Nā manaʻolana hoʻomohala: Ma muli o nā ʻano like ʻole o 9-Methyl-9H-beta-carboline, ua loaʻa i kona hoʻomohala ʻana ka nānā nui ʻia a he ākea ka noiʻi a me nā manaʻolana noi.
Nā noi
Hoʻohana nui ʻia ʻo 9-Me-BC ma ke ʻano he mea hoʻonui ʻike a me ka neuroprotectant. Ua ʻimi nui ʻia no kona hiki ke hoʻomaikaʻi i ka hoʻomanaʻo, ke aʻo ʻana, a me ka hana noʻonoʻo holoʻokoʻa. Eia kekahi, ʻo nā waiwai neuroprotective o 9-Me-BC e ʻae iā ia e pale i nā neurons mai ka hōʻino a kākoʻo i ke olakino o ka lolo. Hoʻohana nui ʻia ʻo 9-Methyl-β-carboline i nā ʻoihana lāʻau lapaʻau, pesticide, a me ka dye ma ke ʻano he mea maka a me ka waena. Eia kekahi, hiki ke hoʻohana ʻia e synthesize i nā pūhui biologically active, e like me nā mea me nā hopena antibacterial a me anti-inflammatory.
