5-Amino-1-methylquinolinium chloride CAS No.:42464-96-0 98.0% maʻemaʻe min. | mea hana mea hoʻohui

ʻO 5-Amino-1-methylquinolinium chloride kahi enzyme i hoʻonui nui ʻia i ka wā ʻelemakule o nā ʻiʻo iwi a pili pū me ka hoʻoponopono ʻana i ka pōʻino o ke ala NAD+, ka hana sirtuin1 dysregulated, a me ka hoʻonui ʻana i ka senescence o nā cell stem muscle. Hoʻolaha ka 5-Amino-1-methylquinolinium chloride i ka hoʻokaʻawale ʻana o ka myoblast i loko o ka vitro a hoʻonui i ka fusion a me ka hana hou ʻana o nā cell stem muscle i nā ʻiole ʻelemakule. ʻO 5-Amino-1-methylquinolinium chloride kekahi mea hoʻopaʻa ikaika o ka nicotinamide N-methyltransferase (NNMT), e hoʻopaʻa koho ana i nā koena kahua hoʻopaʻa substrate NNMT. Hoʻolaha ka 5-Amino-1-methylquinolinium chloride i ka hoʻokaʻawale ʻana o ka myoblast i loko o ka vitro a hoʻonui i ka fusion a me ka hana hou ʻana o nā cell stem muscle i nā ʻiole ʻelemakule. I waena o lākou, ua ʻike hou ʻia ka enzyme cytosolic nicotinamide N-methyltransferase (NNMT) e hoʻoponopono i nā pae o nā precursors nicotinamide e pono ai no ka biosynthesis NAD+, a no laila he kuleana koʻikoʻi ia i ka hoʻoponopono ʻana i ke ala salvage NAD+ a me ka metabolism cellular.

Hana ʻo 5-Amino-1-Methylquinolinium Chloride i loko o kāu microbiome e hōʻemi i ka ʻiʻo adipose (momona) a kōkua iā ʻoe e lilo i ke kaumaha. Ke hōʻiliʻili ʻia nā hunaola momona keu, hana nui kou kino i kahi enzyme i ʻike ʻia ʻo NNMT (nicotinamide N-methyltransferase). ʻO ka nui o ka NNMT, ʻo ka nui o kou kino e hoʻonui i ka mumū a mālama i ka momona. Hoʻopaʻa ʻo 5-Amino-1-Methylquinolinium Chloride i ka NNMT, e ʻae ana i kou kino e hoʻokuʻu i ke kaumaha keu.