Mea hana pauka 7,8-Dihydroxyflavone (7,8-DHF) CAS No.: 38183-03-8 98.0% maʻemaʻe min. no nā mea hoʻohui
Wikiō Huahana
Nā Palena Huahana
| Inoa huahana | 7,8-Dihydroxyflavone |
| Inoa ʻē aʻe | 7,8-DIHYDROXYFLAVONE; 7,8-dihydroxy-2-phenyl-4-benzopyrone; DIHYDROXYFLAVONE, 7,8-(RG); 7,8-Dihydroxyflavone hydrate; 7,8-dihydroxy-2-phenyl-1-benzopyran-4-one |
| Helu CAS. | 38183-03-8 |
| ʻO ke ʻano molekole | C15H10O4 |
| Kaumaha molekole | 254.24 |
| Maʻemaʻe | 98.0% |
| helehelena | Pauka melemele |
| Noi | Mea Hoʻohui Meaʻai Maka |
Hoʻolauna huahana
ʻO 7,8-Dihydroxyflavone, i ʻike ʻia hoʻi ʻo 7,8-DHF, he flavonoid kūlohelohe ia i loaʻa i nā ʻano mea kanu like ʻole, me Tridacna tridacna. ʻIke ʻia no kona mau waiwai antioxidant a me neurotrophic, ʻo kekahi o nā mea hoihoi loa o 7,8-dihydroxyflavone ʻo ia kona hiki ke kākoʻo i ke olakino o ka lolo a hoʻonui i ka hana cognitive. Hōʻike ka noiʻi e hana ana kēia hui ma ke ʻano he neurotrophin ikaika, e hoʻoulu ana i ka ulu ʻana a me ke ola ʻana o nā neurons i loko o ka lolo. Ua hōʻike nā haʻawina i nā holoholona hoʻokolohua e hoʻomaikaʻi nui ka 7,8-DHF i ka hoʻomanaʻo a me nā hiki ke aʻo. Ma ka hoʻolaha ʻana i ka hoʻokumu ʻana o nā pilina synaptic hou a me ka hoʻonui ʻana i ke kamaʻilio ʻana ma waena o nā cell lolo, hoʻohiki kēia hui e wehe i ko mākou hiki ke noʻonoʻo. Eia kekahi, launa pū ka 7,8-dihydroxyflavone me nā receptors serotonin o ka lolo, e pili ana i ka hoʻoponopono ʻana i ke ʻano. Ma ka hoʻololi ʻana i kēia mau receptors, hiki paha iā ia ke hōʻemi i nā hōʻailona o ka hopohopo a me ke kaumaha.
Hiʻona
(1) Maʻemaʻe kiʻekiʻe: Hiki i ka 7,8-Dihydroxyflavone ke loaʻa nā huahana maʻemaʻe kiʻekiʻe ma o ka unuhi kūlohelohe a me ke kaʻina hana maikaʻi. ʻO ke ʻano o ka maʻemaʻe kiʻekiʻe ʻo ia hoʻi ka bioavailability maikaʻi a me nā hopena maikaʻi ʻole.
(2) Palekana: He huahana kūlohelohe ka 7,8-Dihydroxyflavone i hōʻoia ʻia he palekana no nā kānaka. I loko o ka pae dosage, ʻaʻohe ona ʻawahia a i ʻole nā hopena ʻaoʻao.
(3) Paʻa: Loaʻa i ka 7,8-Dihydroxyflavone ke kūpaʻa maikaʻi a hiki ke mālama i kāna hana a me kona hopena ma lalo o nā kūlana kaiapuni a me nā kūlana mālama like ʻole.
(4) Maʻalahi e omo: Hiki ke omo koke ʻia ka 7,8-Dihydroxyflavone e ke kino o ke kanaka, komo i ke kahe koko ma o ke ala ʻōpū, a hāʻawi i nā ʻiʻo a me nā ʻōpū like ʻole.
Nā noi
ʻO 7,8-DHF, ma ke ʻano he mea hoʻoulu mole liʻiliʻi kūpono o ka mea loaʻa TrkB, hiki ke pāʻani i ke kuleana o ka pale ʻana i nā neuron, ka hana hou ʻana o nā neuron, ka hoʻoponopono ʻana i ka plasticity synaptic, a me nā mea ʻē aʻe ma o ka hoʻohālike ʻana i ka hoʻopaʻa ʻana o BDNF iā TrkB a me ka hoʻoulu ʻana i nā ala hōʻailona ma lalo, i mea e hoʻomaikaʻi nui ai i nā hōʻailona o ke aʻo ʻana i ka naʻau a me ka emi ʻana o ka hoʻomanaʻo spatial, ka emi ʻana o ka hiki ke noʻonoʻo, ka emi ʻana o ka hana motor a me nā hōʻailona ʻē aʻe o ka maʻi ʻōnaehana nerve e like me ka maʻi Alzheimer a i ʻole nā mea hoʻohālike holoholona ʻelemakule, A hōʻoluʻolu i nā phenotypes pili o ka maʻi noʻonoʻo a me nā holoholona momona. I kēia manawa, a hiki i kēia manawa, ʻaʻohe hopena ʻino koʻikoʻi o 7,8-DHF i loaʻa i nā holoholona hoʻokolohua. Loaʻa iā 7,8-DHF ka hiki a me ka waiwai nui i ka pale ʻana a me ka mālama ʻana i nā pilikia e pili ana iā BDNF/TrkB.
