Mea hana pauka 1,4-DihydronicotinaMide Riboside CAS No.:19132-12-8 98% maʻemaʻe min. no nā mea hoʻohui
Nā Palena Huahana
| Inoa huahana | 1,4-DihydronicotinaMide Riboside |
| Inoa ʻē aʻe | 1,4-DIHYDRONICOTINAMIDE RIBOSIDE1-[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,4-dihydropyridine-3-carboxamideSCHEMBL188493711-[(3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-4H-PYRIDINE-3-CARBOXAMIDE |
| Helu CAS. | 19132-12-8 |
| ʻO ke ʻano molekole | C11H16N2O5 |
| Kaumaha molekole | 256.26 |
| Maʻemaʻe | 98% |
| helehelena | Pauka keʻokeʻo |
| Hoʻopili ʻana | 1kg/ʻeke; 25kg/pahu |
| Noi | Nā mea hoʻohui meaʻai maka |
Hoʻolauna huahana
ʻO 1,4-dihydronicotinamide riboside, i ʻike ʻia hoʻi ʻo NRH.ʻO ke ʻano i hoʻemi ʻia o NRH kahi mea hoʻomaka NAD + ikaika e kōkua ai e hoʻopiha hou i kona mau pae i loko o ke kelepona.
ʻO ka mea mua a me ka mea nui loa, he mea nui e hoʻomaopopo i ke kuleana o NAD+ i loko o ke kino. ʻO NAD+ kahi coenzyme e pili ana i nā kaʻina hana cellular he nui, me ka metabolism ikehu, ka hoʻoponopono DNA, a me ka hōʻike ʻana o nā gene. I ko kākou ʻelemakule ʻana, e emi ana ko kākou pae o NAD+, kahi i pili i ke kaʻina hana ʻelemakule a me nā maʻi e pili ana i ka ʻelemakule. Ua alakaʻi kēia i ka hoihoi nui i ka ʻike ʻana i nā molekala e hiki ke hoʻonui i nā pae NAD+ i loko o ke kino, a ʻo 1,4-dihydronicotinamide riboside kekahi o ia mau molekala.
He mea hoʻomākaukau ikaika ʻo 1,4-dihydronicotinamide riboside no NAD+, a ua hōʻike ʻia e ka noiʻi hiki iā ia ke hoʻokiʻekiʻe pono i nā pae NAD+ i loko o nā cell. Ua alakaʻi kēia i ka kuhi ʻana he hiki i ka hoʻopihapiha ʻana o 1,4-dihydronicotinamide riboside ke loaʻa ka hiki ke hoʻōla i nā ʻano maʻi like ʻole, me nā maʻi metabolic, nā maʻi neurodegenerative, a me ka emi ʻana e pili ana i ka ʻelemakule.
ʻOiaʻiʻo, aia nā hōʻike e hōʻike ana he ʻoi aku ka maikaʻi o ka 1,4-dihydronicotinamide riboside ma mua o kona molekole makua, ʻo nicotinamide riboside, i ka hoʻonui ʻana i nā pae NAD+. ʻO kēia no ka mea he mea hoʻemi ikaika ka 1,4-dihydronicotinamide riboside, ʻo ia hoʻi, ʻoi aku ka maikaʻi o ka hāʻawi ʻana i nā electrons i ke ala synthesis NAD+. ʻO ka hopena, loaʻa iā ia ka hiki ke hoʻoulu maikaʻi i ka hana ʻana o ka NAD+ cellular.
Ma waho aʻe o kāna kuleana i ka biosynthesis NAD+, loaʻa pū i ka 1,4-dihydronicotinamide riboside nā waiwai antioxidant. ʻO ke kaumaha oxidative, ka hopena o kahi kaulike ʻole ma waena o nā radical free a me nā antioxidants i loko o ke kino, ua pili ia i nā maʻi he nui, me ke kanesa, nā maʻi cardiovascular, a me nā maʻi neurodegenerative. Ma ka scavenging free radicals a me ka hōʻemi ʻana i ka pōʻino oxidative, hiki i ka 1,4-dihydronicotinamide riboside ke hāʻawi i nā pono olakino hou aʻe ma mua o kona kuleana ma ke ʻano he precursor NAD+.
Hiʻona
(1) Maʻemaʻe kiʻekiʻe: Hiki i ka 1,4-dihydronicotinamide riboside ke loaʻa nā huahana maʻemaʻe kiʻekiʻe ma o nā kaʻina hana hana i hoʻomaʻemaʻe ʻia. ʻO ke ʻano o ka maʻemaʻe kiʻekiʻe ʻo ia hoʻi ka bioavailability maikaʻi a me nā hopena maikaʻi ʻole.
(2) Palekana: ʻO 1,4-dihydronicotinamide riboside kahi huahana kūlohelohe i hōʻoia ʻia he palekana no ke kino kanaka.
(3) Paʻa: Loaʻa i ka 1,4-dihydronicotinamide riboside ke kūpaʻa maikaʻi a hiki ke mālama i kāna hana a me ka hopena ma lalo o nā ʻano like ʻole a me nā kūlana mālama.
Nā noi
ʻO 1,4-Dihydronicotinamide ke ʻano hoʻemi ʻia o ka nicotinamide riboside. Hiki iā ia ke ola ma nā ʻano oxidized a me nā ʻano hoʻemi ʻia a he mea mua ia no ka NAD (nicotinamide adenine dinucleotide) i ʻike hou ʻia, i loaʻa ma ke ʻano he mea hoʻohui, me NRH he mea mua NAD+ ikaika a wikiwiki hoʻi ma mua o NR.
