Mea hana pauka Oleoylethanolamide (OEA) CAS No.: 111-58-0 98%,85% maʻemaʻe min. no nā mea hoʻohui

ʻO Oleoylethanolamide kahi hui amide lua i haku ʻia me ka waikawa oleic lipophilic a me ka ethanolamine hydrophilic. ʻO Oleoylethanolamide kahi mole lipid kūlohelohe i nā ʻiʻo holoholona a me nā mea kanu ʻē aʻe. Loaʻa nui ia i nā ʻiʻo holoholona a me nā mea kanu e like me ka pauka koko, ka soybeans, a me nā nati, akā haʻahaʻa loa kona ʻike. Ke loli wale ke kaiapuni o waho a hoʻoulu ʻia paha ka meaʻai, ʻo nā ʻiʻo cell o ke kino wale nō a laila e hana hou ʻia ai kēia mea.

Ma ka mahana o ka lumi, he mea paʻa keʻokeʻo ʻo Oleoylethanolamide me kahi kiko heheʻe ma kahi o 50°C. He maʻalahi ka hoʻoheheʻe ʻia i loko o nā mea hoʻoheheʻe waiʻona e like me ka methanol a me ka ethanol, ʻoi aku ka maʻalahi o ka hoʻoheheʻe ʻia i loko o nā mea hoʻoheheʻe non-polar e like me ka n-hexane a me ka ether, a ʻaʻole hoʻoheheʻe ʻia i ka wai. ʻO ka OEA kahi mole amphiphilic i hoʻohana mau ʻia ma ke ʻano he surfactant a me ka detergent i ka ʻoihana kemika. Eia nō naʻe, ua ʻike ʻia nā noiʻi hou aʻe hiki i ka OEA ke lawelawe ma ke ʻano he mole hōʻailona lipid i loko o ke axis gut-brain a hōʻike i kahi moʻo o nā hana olaola i loko o ke kino, me: ka kaohi ʻana i ka makemake, ka hoʻomaikaʻi ʻana i ka metabolism lipid, ka hoʻonui ʻana i ka hoʻomanaʻo a me ka ʻike a me nā hana ʻē aʻe. I waena o lākou, ua loaʻa i nā hana a Oleoylethanolamide o ka kaohi ʻana i ka makemake a me ka hoʻomaikaʻi ʻana i ka metabolism lipid ka mea i loaʻa ka nānā nui ʻia.

Hiki i ka Oleoylethanolamide ke hoʻoponopono i ka ʻai ʻana a me ka homeostasis ikehu ma ka hoʻoulu ʻana i ka peroxisome proliferator-activated receptor-α. Eia kekahi, hōʻike ʻo Oleoylethanolamide i nā hana ʻē aʻe e pili ana i ke olakino, me ka hoʻololi ʻana i ka hana hoʻololi ma ke ala hōʻailona lysosomal-to-nuclear e pili ana me ka hoʻoponopono lōʻihi a me ka pale ʻana i nā aʻalolo e kāohi ana i nā ʻano kaumaha. Hōʻike pū ka noiʻi he hopena neuroprotective paha ʻo Oleoylethanolamide. I loko o nā hiʻohiʻona holoholona, ​​​​ua ʻike ʻia e hōʻemi i ka pōʻino mai ka hahau ʻana a me ka ʻeha o ka lolo traumatic. ʻO ka hopena hoʻoponopono o Oleoylethanolamide e pili ana i kona nakinaki ʻana iā PPARα, kahi e dimerizes me ka retinoid X receptor (RXR) a hoʻāla iā ia ma ke ʻano he kumu transcription ikaika e pili ana i ka homeostasis ikehu i hui pū ʻia, ka metabolism lipid, autophagy, a me ka mumū. nā pahuhopu downstream.