Mea hana pauka Nefiracetam CAS No.: 77191-36-7 99% maʻemaʻe min. no nā mea hoʻohui
Wikiō Huahana
Nā Palena Huahana
| Inoa huahana | ʻO Nefiracetam |
| Inoa ʻē aʻe | n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamide;NEFIRACETAM; 2-oxo-1-pyrrolidinylaceticacid,2,6-dimethylanilide; dm9384; n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamid;DM-9384,(2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide); DMMPA |
| Helu CAS. | 77191-36-7 |
| ʻO ke ʻano molekole | C14H18N2O2 |
| Kaumaha molekole | 246.3 |
| Maʻemaʻe | 99.0% |
| helehelena | Pauka keʻokeʻo |
| Hoʻopili ʻana | 25 kg/barela |
| Noi | nootropic |
Hoʻolauna huahana
No ka ʻohana piracetam ʻo Nefiracetam, kahi papa o nā lāʻau lapaʻau i ʻike ʻia no ko lākou mau waiwai hoʻonui ʻike. Ua hoʻohui mua ʻia ʻo Nefiracetam i ka hoʻomaka ʻana o nā makahiki 1980 a ua huki koke ʻia ka manaʻo ma muli o kāna ʻano hana kūikawā a me nā noi therapeutic hiki. Manaʻo ʻia kēia hui racemic e hoʻopilikia i nā neurotransmitters a me nā mea loaʻa i loko o ka lolo, e hoʻolaha ana i nā hiki ke hoʻomaikaʻi ʻia. Hoʻopilikia nui ʻo Nefiracetam i nā pae lolo o ka acetylcholine, kahi neurotransmitter koʻikoʻi kuleana no ka hoʻomanaʻo, ke aʻo ʻana, a me ka hana ʻike. Ma ka hoʻololi ʻana i nā mea loaʻa acetylcholine, hoʻolaha ʻo nefiracetam i ka hoʻonui ʻana i ka kamaʻilio ma waena o nā neurons, no laila e hoʻonui ai i ka plasticity synaptic a hoʻomaikaʻi i ka paʻa ʻana o ka hoʻomanaʻo. Eia kekahi, launa pū ʻo nefiracetam me nā mea loaʻa gamma-aminobutyric acid (GABA) e kōkua i ke kaulike ʻana o ka neurotransmitter milieu. Ma ka hoʻopilikia maikaʻi ʻana i nā neurotransmitters excitatory a me inhibitory, kōkua ʻo nefiracetam i ka mālama ʻana i ka hana maikaʻi loa o ka lolo, no laila e hoʻomaikaʻi ana i ka nānā ʻana, ka nānā ʻana, a me ka hana ʻike holoʻokoʻa.
Hiʻona
(1) Maʻemaʻe kiʻekiʻe: Hiki iā Nefiracetam ke loaʻa nā huahana maʻemaʻe kiʻekiʻe ma o nā kaʻina hana hoʻomaʻemaʻe. ʻO ke ʻano o ka maʻemaʻe kiʻekiʻe ʻoi aku ka maikaʻi o ka bioavailability a me nā hopena maikaʻi ʻole.
(2) Palekana: Palekana kiʻekiʻe, kakaikahi nā hopena maikaʻi ʻole.
(3) Paʻa: He kūpaʻa maikaʻi ko Nefiracetam a hiki ke mālama i kāna hana a me kona hopena ma lalo o nā ʻano like ʻole a me nā kūlana mālama.
Nā noi
ʻO Nefiracetam kahi derivative hydrophobic o piracetam, kahi i manaʻo nui ʻia he mea kuleana no ka ʻike ʻana o nā kahawai calcium i loko o ke kino a me ka hoʻoili pololei ʻole ʻana o nā mea hōʻailona hoʻonāukiuki ma ke ʻano he agonist hapa o nā kahawai ion calcium. Kahi hoʻopaʻa Glycine o ka receptor NDMA. Ma o kona hopena ma ka cortex cerebral, hiki i ka nefiracetam ke hoʻonui i nā hiki cognitive a pale i ke aʻo ʻana a me ka hoʻomanaʻo ʻana. ʻAʻohe ona waiwai agonist receptor muscarinic a i ʻole antagonist, ʻaʻole hoʻi e kāohi i ka hana acetylcholinease. No laila, ua hoʻokō ʻia kāna mau hopena anti-amnestic a me ka hoʻonui ʻana i ka hoʻomanaʻo ma ka hoʻomaikaʻi ʻana i ka hoʻokuʻu ʻana o ka acetylcholine i loko o ka cortex cerebral.
