YDL223C (HBT1) mea hana pauka CAS No.: 489408-02-8 99% maemae min.no nā mea hoʻohui
Nā Kūlana Huahana
| Inoa mea kūʻai | HBT1 |
| inoa ʻē aʻe | YDL223C |
| CAS No. | 489408-02-8 |
| ʻAno molekala | C16H17F3N4O2S |
| Kaumaha molekula | 386.40 |
| Maemae | 99.0% |
| Ka nana aku | Paʻa melemele māmā |
| Hoʻopili | 1kg no ka ʻeke 25kg no ka pahu |
| Palapala noi | nootropics |
Hoʻolauna huahana
Hoʻopaʻa ka HBT1 i ka ligand-binding domain o ka α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA-R) ma ke ʻano glutamate-dependent.ʻO ia ke ʻano o ka HBT1 he mole e hiki ke hoʻopaʻa wale i nā wahi kikoʻī ma ka protein AMPA-R ke loaʻa ka glutamate, a ʻo kēia paʻa e kōkua i ka hoʻoponopono ʻana i ka hana o ka protein.Hōʻike ʻia nā mea loaʻa AMPA i loko o ka ʻōnaehana nerve waena a pāʻani i nā kuleana koʻikoʻi i ka kamaʻilio neuronal, ka hana sensory, a me ke aʻo ʻana, hoʻomanaʻo, a me ka synaptic plasticity.ʻO nā mea loaʻa AMPA nā mea kōkua nui i ka neurotransmission excitatory, hoʻopili wikiwiki, wikiwiki desensitized excitation o nā synapses he nui, a komo i nā pane mua o nā wahi synaptic i ka glutamate.Hoʻopili pinepine ʻia nā mea loaʻa AMPA me nā mea loaʻa NMDA i nā synapses, a hui pū lākou e hāpai i nā kaʻina hana plasticity synaptic e pili ana i ke aʻo ʻana, hoʻomanaʻo, excitotoxicity, a me neuroprotection.
Hiʻona
ʻO ka brain-derived neurotrophic factor (BDNF) he mea neurotrophic e hana nui i ka mālama ʻana a me ka hoʻonui ʻana i nā neurons, a he ikaika a nui nā hopena i ka hoʻonui ʻana, ka ʻokoʻa, ke ola a me ka make o nā neuronal a me nā pūnaewele non-neuronal. he neurotransmitter modulator a hāʻawi i ka neuronal plasticity no ke aʻo ʻana a me ka hoʻomanaʻo.No laila he mea nui ia i ke olakino a me ka maikaʻi o ka ʻōnaehana nerve.Hiki i ka hoʻonui ʻana i ka BDNF ke kōkua i ka mālama ʻana a me ka pale ʻana i nā maʻi he nui.
Nā noi
ʻO HBT1 kahi mea hoʻonui hoʻokipa AMPA hou me ka agonism haʻahaʻa i hoʻohālikelike ʻia me LY451395 a me OXP1, hoʻoulu ia i ka hana ʻana o ka brain-derived neurotrophic factor (BDNF), a hōʻike i ka hopena liʻiliʻi i nā neurons Agitation.Hoʻopili ʻo HBT1 i ka ligand-binding domain o AMPA-R ma kahi ʻano hilinaʻi glutamate.Hoʻohui pū lākou i nā kaʻina hana synaptic plasticity e pili ana i ke aʻo ʻana, hoʻomanaʻo, excitability a me neuroprotection.Hiki iā ia ke hoʻomaikaʻi i ka noʻonoʻo a me ka hoʻomanaʻo o ka lolo, a hoʻonui i ka hiki ke aʻo ʻana o nā kānaka.
