Mea hana pauka 5-Aminolevulinic acid phosphate (ALA) CAS No.: 868074-65-1 98% maʻemaʻe min. me ke kumu kūʻai maikaʻi loa
Wikiō Huahana
Nā Palena Huahana
| Inoa huahana | 5-Aminolevulinic acid phosphate |
| Inoa ʻē aʻe | ʻAkika 5-amino-4-oxopentanoic, waikawa phosphoric; ʻAkika 5-aminolevulinic phosphate, 5-ALA phosphate; ʻAkika 5-Amino-4-oxopentanoic phosphate; 5-ʻAminolevulinic acid phosphate; ʻAkika Pentanoic, 5-amino-4-oxo-, phosphate |
| Helu CAS. | 868074-65-1 |
| ʻO ke ʻano molekole | C5H12NO7P |
| Kaumaha molekole | 229.13 |
| Maʻemaʻe | 98.0% |
| helehelena | Pauka keʻokeʻo a keʻokeʻo paha |
| Noi | Mea Hoʻohui Meaʻai Maka |
Hoʻolauna huahana
ʻO ka 5-Aminolevulinic acid phosphate, i ʻike nui ʻia ʻo ALA phosphate, he mea koʻikoʻi ia i ka biosynthesis o ka heme, kahi ʻāpana koʻikoʻi o ka hemoglobin, myoglobin a me nā enzymes like ʻole i loko o ke kino. Hoʻohui ʻia ka ALA phosphate ma o kahi moʻo o nā hopena enzymatic e hana nui ʻia ma mitochondria, nā kikowaena mana o kā mākou mau cell. Hoʻokumu ʻia ia mai ka condensation o glycine a me succinyl-CoA, he mau ʻāpana koʻikoʻi o kā mākou mau ala metabolic. He mea koʻikoʻi ka synthesis o ka heme i ke olakino kanaka no ka mea he kuleana koʻikoʻi kēia mole i ka lawe ʻana i ka oxygen, ka hoʻoili electron a me ka detoxification. ʻO ALA phosphate ka ʻanuʻu palena wikiwiki i ka biosynthesis heme. Ma o kahi moʻo o nā hoʻololi enzymatic, hoʻololi ʻia ka ALA phosphate i porphobilinogen, ka mole mua o ka heme.
Hiʻona
(1) Maʻemaʻe kiʻekiʻe: Hiki ke loaʻa ka 5-aminolevulinic acid phosphate ma ke ʻano he huahana maʻemaʻe kiʻekiʻe ma o nā kaʻina hana hana i hoʻomaʻemaʻe ʻia. ʻO ke ʻano o ka maʻemaʻe kiʻekiʻe ʻo ia hoʻi ka bioavailability maikaʻi a me nā hopena ʻino liʻiliʻi.
(2) Palekana: Ua hōʻoia ʻia ka palekana o ka 5-aminolevulinic acid phosphate no ke kino o ke kanaka.
(3) Paʻa: Loaʻa i ka 5-Aminolevulinic acid phosphate ke kūpaʻa maikaʻi a hiki ke mālama i kāna hana a me ka hopena ma lalo o nā ʻano like ʻole a me nā kūlana mālama.
Nā noi
ʻO ka 5-Aminolevulinic acid phosphate (5-ALA) kahi amino acid kūlohelohe a he mea hana nui i loaʻa i ke ola. ʻO ia ke kumu o nā hui porphyrin a me ke substrate no nā hopena biochemical o chlorophyll, heme a me ka huaora B12. ʻO ka 5-ALA phosphate kahi derivative o 5-ALA a ʻoi aku ka maʻalahi o ka omo ʻana a hoʻohana ʻia e ke kino. ʻO ka lawelawe waha ʻana o 5-ALA phosphate hiki ke hoʻāla i ka myoglobin synthase, hoʻolalelale i ka synthesis o myoglobin i loko o ke kino kanaka, hoʻonui i ka momona o nā ʻiʻo, a hoʻemi i ka momona. Eia kekahi, hiki i ka 5-ALA ke hoʻonui i ka hana o mitochondria i loko o nā cell kanaka, hoʻolaha i ka metabolism, hoʻomaikaʻi i ka pono o ka loaʻa ʻana o ka ikehu, a hoʻemi i ke kō koko a me nā lipids koko. I ka hopena, he mea maikaʻi loa ka 5-ALA phosphate i ke olakino.
