Oleoylethanolamide (OEA) mea hana pauka CAS No.: 111-58-0 98%,85% maemae min. no nā mea hoʻohui

ʻO Oleoylethanolamide kahi pūhui amide lua i haku ʻia me ka lipophilic oleic acid a me ka hydrophilic ethanolamine. ʻO Oleoylethanolamide kahi mole lipid kūlohelohe maoli i loko o nā ʻiʻo holoholona a me nā mea kanu ʻē aʻe. Aia ia i loko o nā ʻiʻo holoholona a me nā mea kanu e like me ka pauka koko, soybeans, a me nā nati, akā he haʻahaʻa loa kona ʻike. Ke hoʻololi wale ʻia ke kaiapuni o waho a hoʻoulu ʻia ka meaʻai, nā ʻiʻo o ke kino o ke kino Ma laila wale nō e hana ʻia ai ka nui o kēia mea.

Ma ka lumi wela, ʻo Oleoylethanolamide kahi paʻa keʻokeʻo me kahi helu heheʻe ma kahi o 50°C. He maʻalahi hiki ke hoʻoheheʻe ʻia i loko o nā mea hoʻoheheʻe ʻawaʻawa e like me ka methanol a me ka ethanol, ʻoi aku ka maʻalahi o ka hoʻoheheʻe ʻana i nā solvents non-polar e like me ka n-hexane a me ka etera, a hiki ʻole ke hoʻoheheʻe ʻia i ka wai. ʻO OEA kahi mole amphiphilic i hoʻohana mau ʻia ma ke ʻano he surfactant a me ka mea holoi ma ka ʻoihana kemika. Eia naʻe, ua ʻike hou ʻia ka noiʻi ʻana e hiki i ka OEA ke lawelawe ma ke ʻano he molelika hōʻailona lipid i ka axis gut-brain a hōʻike i ke ʻano o nā hana olaola i loko o ke kino, ʻo ia hoʻi: ka mālama ʻana i ka ʻai, hoʻomaikaʻi i ka lipid metabolism, hoʻonui i ka hoʻomanaʻo a me ka cognition a me nā hana ʻē aʻe. Ma waena o lākou, ʻo nā hana a Oleoylethanolamide no ka mālama ʻana i ka makemake a me ka hoʻomaikaʻi ʻana i ka lipid metabolism i loaʻa i ka manaʻo nui loa.

Hiki i ka Oleoylethanolamide ke hoʻoponopono i ka lawe ʻana i ka meaʻai a me ka homeostasis ikehu ma o ka hoʻoulu ʻana i ka peroxisome proliferator-activated receptor-α. Eia kekahi, hōʻike ʻo Oleoylethanolamide i nā hana ʻē aʻe e pili ana i ke olakino, me ka hoʻololi ʻana i ka hana converter ma ke ala hōʻailona lysosomal-to-nuclear e pili ana i ka hoʻoponopono lōʻihi a me ka pale ʻana i nā aʻalolo e hoʻomalu i nā ʻano depressive. Hōʻike pū ka noiʻi e loaʻa paha i ka Oleoylethanolamide nā hopena neuroprotective. Ma nā ʻano holoholona, ​​ua ʻike ʻia e hōʻemi i ka pōʻino mai ka hahau ʻana a me ka ʻeha lolo. Hoʻopili ʻia ka hopena hoʻoponopono o Oleoylethanolamide i kona hoʻopaʻa ʻana iā PPARα, ka mea dimerizes me ka retinoid X receptor (RXR) a hoʻōla iā ia ma ke ʻano he kumu transcription potent i komo i ka homeostasis ikehu hui, lipid metabolism, autophagy, a me ka mumū. nā pahu hopu i lalo.