ʻO 7,8-Dihydroxyflavone kahi hui kūlohelohe i loaʻa i nā mea kanu i loaʻa ka nānā nui ʻia no kona mau pono kūpono i ka hana o ka lolo a me ka hoʻomanaʻo. No kēia hui flavone kahi papa o nā kemika i kapa ʻia ʻo flavonoids, i ʻike ʻia no ko lākou mau waiwai antioxidant a me anti-inflammatory. Ua hōʻike ʻia e ka noiʻi he nui nā hopena maikaʻi o 7,8-dihydroxyflavone i ka lolo.
He hui ikaika a maʻalahi hoʻi ʻo 7,8-Dihydroxyflavone no ka ʻohana flavonoid. He mau hui kūlohelohe nā Flavonoids i hoʻolaha nui ʻia i nā mea kanu a he mau kuleana koʻikoʻi i nā ʻano hana olaola like ʻole. ʻO kekahi o nā ʻano kupaianaha o 7,8-dihydroxyflavone ʻo kona hiki ke launa pū me a hoʻoponopono i nā protein a me nā enzymes i loko o ke kino, kahi i hoʻāla ai i ka hoihoi nui i ke kaiāulu ʻepekema.
Ua hōʻike ʻia e ka noiʻi he hiki i ka hui 7,8-dihydroxyflavone ke loaʻa nā pono olakino, nona nā waiwai antioxidant, anti-inflammatory a me neuroprotective. I waena o lākou, ʻo ka hana antioxidant ikaika o 7,8-dihydroxyflavone e hiki ai iā ia ke ʻohi i nā radical manuahi ʻino i loko o ke kino a pale i ke kaumaha oxidative mai ka hōʻino ʻana i nā cell a me nā maʻi like ʻole. He mea hoʻoikaika ka noiʻi i hana ʻia a hiki i kēia manawa ma 7,8-dihydroxyflavones, akā pono ka noiʻi hou aku e hoʻoholo i ka pono a me ka palekana o 7,8-dihydroxyflavones no ka hoʻohana ʻana i nā kānaka. Eia nō naʻe, he manaʻolana nui kēia hui flavonoid ma ke ʻano he mea hoʻohui meaʻai a i ʻole he moho lāʻau lapaʻau i ka wā e hiki mai ana.
He hui kūlohelohe ʻo 7,8-Dihydroxyflavone, i ʻike ʻia hoʻi ʻo 7,8-DHF, i loaʻa ka nui o ka nānā ʻana i nā makahiki i hala iho nei no kona mau pono kūpono i ke olakino kanaka.
No ka ʻohana flavonoid kēia hui kūlohelohe a loaʻa i nā ʻano mea kanu like ʻole, me ke aʻa o Scutellaria baicalensis.
1. Hoʻomaikaʻi i ka hana noʻonoʻo
Ua hōʻike ʻia ma ka noiʻi e hana ana kēia hui ma ke ʻano he agonist TrkB, ʻo ia hoʻi ke hoʻoulu nei i nā mea loaʻa TrkB i loko o ka lolo. ʻO kēia mau mea loaʻa ke kuleana no ka hoʻolaha ʻana i ka ulu ʻana a me ke ola ʻana o nā neurons, a me ka hoʻonui ʻana i ka plasticity synaptic -- ka hiki o ka lolo ke hoʻololi a hoʻololi. Ma ka hoʻoulu ʻana i nā mea loaʻa TrkB, ua hōʻike ʻia ʻo 7,8-dihydroxyflavone e hoʻomaikaʻi i ka hoʻomanaʻo a me ka ʻike. ʻO kēia ka mea e lilo ai ia i mea lapaʻau kūpono no ka mālama ʻana i nā maʻi neurodegenerative e like me ka maʻi Alzheimer.
2. Ka hopena antidepressant
Ma ka hoʻoulu ʻana i nā mea loaʻa TrkB, hoʻolaha ka hui i ka ulu ʻana o nā neurons hou ma ka hippocampus, kahi ʻāpana o ka lolo e pili ana i ka hoʻoponopono ʻana i ke ʻano. Ua hōʻike ʻia nā haʻawina hoʻohālike holoholona e hiki i ka 7,8-dihydroxyflavone ke hōʻemi i nā hōʻailona kaumaha a hoʻonui i ke kūpaʻa ʻana i ke kaumaha. Hōʻike kēia mau ʻike e hiki ke hoʻohana ʻia kēia hui ma ke ʻano he koho kūlohelohe i nā antidepressants kuʻuna.
3. Nā waiwai anti-inflammatory a me ka hiki ke antioxidant
He antioxidant ikaika ka 7,8-Dihydroxyflavone e kōkua ana i ka pale ʻana i nā cell mai ke kaumaha oxidative i hoʻokumu ʻia e nā radical free. Hoʻemi kēia pale i ka pilikia o nā maʻi maʻi a hoʻolohi i ke kaʻina hana ʻelemakule.
Hiki i ka mumū o ka lolo ke kōkua i ka ulu ʻana a me ka holomua ʻana o nā maʻi neurological like ʻole, me ka maʻi Parkinson a me ka sclerosis maha. Hōʻike ka noiʻi he mau waiwai anti-inflammatory ko 7,8-DHF e kōkua i ka hōʻemi ʻana i ka mumū i loko o ka lolo a pale i ka neurodegeneration. Ma ka pale ʻana i ka hana ʻana o nā mole pro-inflammatory, hiki i ka hui ke loaʻa ka hiki ke hōʻemi i nā hōʻailona a hoʻolohi i ka holomua o kēia mau maʻi hoʻonāwaliwali.
4. Loaʻa ka hiki ke mālama i nā maʻi hopohopo
Ua hōʻike ʻia nā haʻawina holoholona e hiki i ka hui ke hōʻemi i ke ʻano hopohopo ma o ka hoʻoulu ʻana i nā mea loaʻa TrkB ma ka amygdala, kahi ʻāpana o ka lolo e pili ana i ka makaʻu a me nā pane hopohopo. Ma ka hoʻololi ʻana i ka hana o kēia mau mea loaʻa, hiki i ka 7,8-dihydroxyflavones ke hāʻawi i kahi ala kūlohelohe a maikaʻi hoʻi e hoʻokele ai i ka hopohopo me ka ʻole o nā hopena ʻaoʻao e pili ana me nā lāʻau anti-anxiety kuʻuna.
Ma mua o ke komo ʻana i nā kumu meaʻai, e hoʻomaopopo kākou i ke ʻano maoli o ka 7,8-dihydroxyflavone. He flavonoid kūlohelohe ia no ka papa o nā flavonoids. ʻO nā Flavonoids nā hui mea kanu i ʻike ʻia no ko lākou mau waiwai antioxidant, e kōkua ana i ka pale ʻana i nā cell mai nā radical free ʻino.
I kēia manawa, e ʻimi kākou i kekahi mau meaʻai i loaʻa ka nui o 7,8-dihydroxyflavone:
1. Nā hua citrus
ʻO kekahi o nā kumu maikaʻi loa o 7,8-dihydroxyflavones nā hua citrus e like me nā ʻalani, nā lemona, ka grapefruit a me nā lime. ʻAʻole wale kēia mau hua i waiwai i ka huaora C, akā loaʻa pū kekahi mau flavonoids, me 7,8-dihydroxyflavone.
2. Nā hua
Ua kaulana nā hua e like me nā blueberries, nā ʻōpena, nā raspberries, a me nā blackberries no ko lākou nui o nā antioxidants. He kumu maikaʻi nō hoʻi kēia mau hua ʻono no ka 7,8-dihydroxyflavone, e hāʻawi ana iā ʻoe i nā pono olakino pālua.
3. Kokoleka ʻeleʻele
He nūhou maikaʻi no ka poʻe aloha kokoleka! ʻO ke kokoleka ʻeleʻele, ʻoiai hoʻi kekahi me ka nui o ka koko, aia ka nui o 7,8-dihydroxyflavonoids. Eia nō naʻe, e koho i nā ʻano me ka liʻiliʻi loa o ke kō i hoʻohui ʻia e loaʻa ai nā pono piha.
4. Kī ʻōmaʻomaʻo
Ma waho aʻe o ka lilo ʻana i mea inu kaulana, waiwai nui ke kī ʻōmaʻomaʻo i nā flavonoids, me 7,8-dihydroxyflavone. Hiki i ka ʻai mau ʻana i ke kī ʻōmaʻomaʻo ke kōkua i ka hoʻonui ʻana i kāu lawe ʻana i nā antioxidants a kākoʻo i ke olakino holoʻokoʻa.
5. Soy
Inā ʻoe e ʻimi nei i kahi kumu mea kanu o 7,8-dihydroxyflavone, he koho maikaʻi loa ka soy. ʻAʻole wale lākou i kiʻekiʻe i ka protein, akā loaʻa pū kekahi mau flavonoids i loko e hāʻawi i ko lākou mau waiwai pono.
6. Nā lau ʻōmaʻomaʻo lau
ʻAʻole wale nā mea kanu e like me ke kale, spinach, a me ka broccoli he haʻahaʻa i nā calorie, akā waiwai nui hoʻi i nā antioxidants. ʻO kēia mau lau ʻōmaʻomaʻo he kumu maikaʻi loa ia o 7,8-dihydroxyflavone, a me nā meaola koʻikoʻi ʻē aʻe.
7. Waina ʻulaʻula
ʻAloha! ʻO ka inu ʻana i ka waina ʻulaʻula me ka awelika, aia kahi ʻano flavonoid i kapa ʻia ʻo resveratrol, nona ka 7,8-dihydroxyflavone. Ua manaʻo ʻia kēia hui e kōkua i nā pono cardiovascular e pili ana me ka inu ʻana i ka waina ʻulaʻula me ka awelika.
ʻO ka hoʻokomo ʻana i kēia mau meaʻai i kāu meaʻai e hiki ke hāʻawi iā ʻoe i nā pono he nui e pili ana me 7,8-dihydroxyflavone.
ʻO 7,8-Dihydroxyflavone, i ʻike ʻia hoʻi ʻo DHF a i ʻole baicalein, he flavonoid kūlohelohe ia i loaʻa i nā ʻano mea kanu like ʻole, me ke aʻa o Scutellaria baicalensis. Ua loaʻa i kēia hui ka nui o ka nānā ʻana i nā makahiki i hala iho nei no kona mau pono olakino a me nā waiwai therapeutic. Eia nō naʻe, i ka noʻonoʻo ʻana i ka palekana o kekahi mea, he mea nui e nānā i nā hōʻike ʻepekema i loaʻa. No laila, palekana anei ʻo 7,8-dihydroxyflavone?
Ma ke ʻano o kona palekana, ua kaupalena ʻia ka noiʻi ʻana ma ka ʻai pololei ʻana o ke kanaka i ka 7,8-dihydroxyflavone. No laila, he mea paʻakikī ka hana ʻana i nā ʻōlelo hoʻoholo e pili ana i kona palekana. Eia nō naʻe, ua hāʻawi nā haʻawina holoholona i kekahi ʻike waiwai i kona hiki ke ʻawahia. ʻAʻole i hōʻike nā ʻano holoholona like ʻole i nā hopena ʻaoʻao koʻikoʻi ma hope o ka lawelawe ʻana i ka DHF, ʻoiai ma nā dosis kiʻekiʻe. Hōʻike kēia e hiki ke ʻae maikaʻi ʻia ka 7,8-dihydroxyflavone, ma ka liʻiliʻi i loko o nā palena i aʻo ʻia.
Eia nō naʻe, pono e akahele i ka wā e huki ai i nā hopena ma muli wale nō o nā haʻawina holoholona. Hiki ke ʻokoʻa loa nā hopena o nā mea ma waena o nā ʻano like ʻole, no laila, pono ke akahele i ka wā e hoʻonui ai i nā hopena i nā kānaka. Eia kekahi, ʻo ka nele o nā haʻawina kanaka lōʻihi piha ua pale i ka loiloi maopopo o kona palekana.
ʻO 7,8-Dihydroxyflavone (7,8-DHF) kahi flavonoid kūlohelohe i loaʻa ka nui o ka nānā ʻana no kona mau pono olakino, akā naʻe, he mea nui loa ia e ʻike i ka nui i ʻōlelo ʻia a me nā ʻōlelo aʻoaʻo i ka wā e hoʻohana ai i ka 7,8-DHF.
He mea nui e kūkākūkā me kahi loea olakino i ka wā e pili ana i ka nui o ka lāʻau o 7,8-DHF, no ka mea, ʻokoʻa paha ka nui kūpono ma muli o nā kumu he nui e like me ka makahiki, ke kaumaha a me nā kūlana olakino kikoʻī. Manaʻo ka noiʻi o kēia manawa i nā koho nui o ka nui, maʻamau he 20 a 60 mg i kēlā me kēia lā. Eia nō naʻe, pono e hoʻomaopopo ʻia ʻaʻole i paʻa kēia mau ʻōlelo aʻoaʻo a hiki ke loli i ka wā e hōʻiliʻili ʻia ai nā hōʻike ʻepekema hou aʻe.
I ke kūʻai ʻana i nā mea hoʻohui meaʻai 7,8-DHF, he mea nui e koho i kahi mea hana kaulana a hilinaʻi hoʻi e hōʻoia i ka palekana a me ka pono o ka huahana. ʻO ka heluhelu ʻana i nā loiloi o nā mea kūʻai aku a me ka nānā ʻana i nā hoʻokolohua lab ʻaoʻao ʻekolu hiki ke kōkua i ka hoʻoholo ʻana i ka hilinaʻi o kahi huahana. He mea nui loa ia e hahai i nā ʻōlelo aʻoaʻo a kāu loea olakino. E hiki iā lākou ke hāʻawi i ke alakaʻi pilikino e pili ana i kāu mōʻaukala olakino a me nā kūlana olakino o kēia manawa. Manaʻo mau ʻia e hoʻomaka me ka mahele haʻahaʻa loa a hoʻonui mālie e like me ka mea e pono ai ma lalo o ka nānā ʻana o kahi loea olakino.
Ma mua o ka hoʻokomo ʻana i ka 7,8-DHF i kāu papa hana o kēlā me kēia lā, he mea nui e makaʻala i nā hopena ʻaoʻao a i ʻole nā pilina lāʻau. ʻOiai ua ʻae maikaʻi ʻia ka 7,8-DHF ma ke ʻano laulā, hiki i kekahi poʻe ke loaʻa i ka ʻeha gastrointestinal iki a i ʻole nā hopena allergies. Eia kekahi, e hōʻoia e hoʻomaopopo i kāu kauka lapaʻau i nā lāʻau lapaʻau a i ʻole nā mea hoʻohui āu e lawe nei i kēia manawa e pale aku i nā pilina hiki. E hoʻomanaʻo i ka lawe ʻana i nā mea hoʻohui e pono mau ma lalo o ke alakaʻi a kahi kauka lapaʻau e hoʻomaikaʻi i kou olakino.
Q: Pehea ka lōʻihi o ka hana ʻana o 7,8-dihydroxyflavoneor?
A: ʻO ka wikiwiki o ka hopena o 7,8-dihydroxyflavone (7,8-DHF) hiki ke ʻokoʻa ma muli o kekahi mau kumu. I nā haʻawina ʻepekema, ua hōʻike ʻia ʻo 7,8-DHF he mau hopena like ʻole, e like me ka hoʻolaha ʻana i ka hoʻokuʻu ʻana o nā kumu neurotrophic a me ka neuroprotection. ʻO ka manawa e pono ai no kēia mau hopena e hōʻike ʻia mai nā hola a i nā lā a ʻoi aku paha, ma muli o ke ʻano hana kikoʻī a me ka pahuhopu o ka hui.
ʻŌlelo Hoʻolaha: No ka ʻike wale nō kēia ʻatikala a ʻaʻole pono e manaʻo ʻia he ʻōlelo aʻoaʻo lapaʻau. E kūkākūkā mau me kahi loea mālama ola ma mua o ka hoʻohana ʻana i nā mea hoʻohui a i ʻole ka hoʻololi ʻana i kāu papa hana mālama ola.
Ka manawa hoʻouna: Iulai-04-2023
