Nefiracetam pauka mea hana CAS No.: 77191-36-7 99% maemae min. no nā mea hoʻohui
Video Huahana
Nā Kūlana Huahana
| inoa huahana | Nefiracetam |
| inoa ʻē aʻe | n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamide;NEFIRACETAM; 2-oxo-1-pyrrolidinylaceticacid, 2,6-dimethylanilide; dm9384; n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamid;DM-9384,(2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide); DMMPA |
| CAS No. | 77191-36-7 |
| ʻAno molekala | C14H18N2O2 |
| Kaumaha molekula | 246.3 |
| Maemae | 99.0% |
| Ka nana aku | Pauda keʻokeʻo |
| Hoʻopili | 25 kg/barela |
| Palapala noi | nootropic |
Hoʻolauna huahana
No ka ʻohana piracetam ka Nefiracetam, kahi papa o nā lāʻau lapaʻau i ʻike ʻia no kā lākou mau waiwai hoʻonui cognitive. Ua hoʻokumu mua ʻia ʻo Nefiracetam i ka 1980s mua a ua huki koke i ka nānā ʻana ma muli o kāna ʻano hana kūikawā a me nā noi therapeutic kūpono. Manaʻo ʻia kēia hui racemic e hoʻopilikia i nā neurotransmitters a me nā mea loaʻa i loko o ka lolo, i ka hopena e hoʻomaikaʻi i ka hiki ke noʻonoʻo. Hoʻopili nui ʻo Nefiracetam i nā pae lolo o acetylcholine, kahi neurotransmitter koʻikoʻi i kuleana no ka hoʻomanaʻo, aʻo ʻana, a me ka hana cognitive. Ma ka hoʻololi ʻana i nā mea hoʻokipa acetylcholine, hoʻonui ka nefiracetam i ka kamaʻilio ma waena o nā neurons, a laila e hoʻonui ai i ka plasticity synaptic a me ka hoʻomaikaʻi ʻana i ka hoʻomanaʻo. Eia kekahi, hoʻopili ka nefiracetam me ka gamma-aminobutyric acid (GABA) receptors e kōkua i ke kaulike ʻana i ka milieu neurotransmitter. Ma ka hopena maikaʻi ʻana i nā neurotransmitters excitatory a me inhibitory, kōkua ka nefiracetam i ka mālama ʻana i ka hana o ka lolo, a laila e hoʻomaikaʻi ai i ka nānā ʻana, ka nānā ʻana, a me ka hana cognitive holoʻokoʻa.
Hiʻona
(1) Maʻemaʻe kiʻekiʻe: Hiki iā Nefiracetam ke loaʻa nā huahana maʻemaʻe kiʻekiʻe ma o ka hoʻomaʻemaʻe ʻana i nā kaʻina hana. ʻO ka maʻemaʻe kiʻekiʻe, ʻoi aku ka maikaʻi o ka bioavailability a me ka liʻiliʻi o nā hopena ʻino.
(2) Palekana: Palekana kiʻekiʻe, liʻiliʻi nā hopena ʻino.
(3) Paʻa: He kūpaʻa maikaʻi ka Nefiracetam a hiki ke mālama i kāna hana a me ka hopena ma lalo o nā kaiapuni likeʻole a me nā kūlana mālama.
Nā noi
ʻO ka Nefiracetam kahi hydrophobic derivative o ka piracetam, ka mea maʻamau i manaʻo ʻia he mea kuleana no ka loaʻa ʻana o nā kahawai calcium i loko o ke kino a me ka hoʻololi ʻole ʻana o nā mea hōʻailona excitatory ma ke ʻano he agonist ʻāpana o nā kaila ion calcium. ʻO ka pae hoʻopaʻa Glycine o ka mea hoʻokipa NDMA. Ma o kona hopena ma ka cerebral cortex, hiki i ka nefiracetam ke hoʻonui i nā mana cognitive a pale i ke aʻo ʻana a me ka hoʻomanaʻo. ʻAʻole loaʻa iā ia ka muscarinic receptor agonist a i ʻole nā mea antagonist, ʻaʻole hoʻi e kāohi i ka hana acetylcholinease. No laila, loaʻa kāna mau hopena anti-amnestic a me ka hoʻonui ʻana i ka hoʻomanaʻo ma o ka hoʻomaikaʻi ʻana i ka hoʻokuʻu ʻana o ka acetylcholine i ka cerebral cortex.
