Mea hana pauka YDL223C (HBT1) CAS No.: 489408-02-8 99% maʻemaʻe min. no nā mea hoʻohui

Hoʻopaʻa ʻo HBT1 i ka ʻāpana hoʻopaʻa ligand o ka α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA-R) ma ke ʻano e pili ana i ka glutamate. ʻO ke ʻano kēia, ʻo HBT1 kahi molekala hiki ke hoʻopaʻa wale i kahi kikoʻī ma ka protein AMPA-R ke loaʻa ka glutamate, a kōkua kēia hoʻopaʻa ʻana i ka hoʻoponopono ʻana i ka hana o ka protein. Hōʻike ʻia nā mea loaʻa AMPA ma loko o ka ʻōnaehana nerve waena a pāʻani i nā kuleana koʻikoʻi i ka kamaʻilio neuronal, ka hana sensory, ke aʻo ʻana, ka hoʻomanaʻo, a me ka plasticity synaptic. ʻO nā mea loaʻa AMPA nā mea kōkua nui i ka neurotransmission excitatory, hoʻoponopono wikiwiki, hoʻēmi koke i ka hoʻonāukiuki ma nā synapses he nui, a pili i nā pane mua i ka glutamate ma nā wahi synaptic. Hoʻopili pinepine ʻia nā mea loaʻa AMPA me nā mea loaʻa NMDA ma nā synapses, a hui pū lākou e hoʻolaha i nā kaʻina hana plasticity synaptic e pili ana i ke aʻo ʻana, ka hoʻomanaʻo, ka excitotoxicity, a me ka neuroprotection. ʻO ka kumu neurotrophic i loaʻa mai ka lolo (BDNF) kahi kumu neurotrophic e pāʻani ana i kahi kuleana koʻikoʻi i ka mālama ʻana a me ka hoʻonui ʻana o nā neurons a he hopena ikaika a he nui nā hopena i ka hoʻonui ʻana, ka hoʻokaʻawale ʻana, ke ola ʻana a me ka make ʻana o nā cell neuronal a me nā non-neuronal. , kahi modulator neurotransmitter e hāʻawi i ka neuronal plasticity i ke aʻo ʻana a me ka hoʻomanaʻo. No laila, he mea nui ia no ke olakino a me ka pono o ka ʻōnaehana nerve.