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huahana

Huipuia 7P pauka mea hana CAS No.: 1890208-58-8 99% maemae min. no nā mea hoʻohui

ʻO ka wehewehe pōkole:

Ua hōʻike ʻia ʻo Compound 7p e hoʻoulu i ka ulu ʻana o GAP-43-positive axons i loko o kahi ʻano holoholona o ka hōʻeha nerve optic, e hōʻike ana i ka hana neurite outgrowth o ka pūhui 7p in vitro e unuhi i ka hoʻoulu ʻana o ka axon regeneration in vivo.


Huahana Huahana

Huahana Huahana

Video Huahana

Nā Kūlana Huahana

inoa huahana

Huina 7P

inoa ʻē aʻe

Huina7P;2-[(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide ;

2-(N-(2-methoxyphenyl)-4-methylphenylsulfonamido)-N-(4-methoxypyridin-3-yl)acetamide

CAS No.

1890208-58-8

ʻAno molekala

C22H23N3O5S

Kaumaha molekula

441.51

Maemae

99.0%

Ka nana aku

Pauda keʻokeʻo

Palapala noi

Nootropic

Hoʻolauna huahana

ʻO ka Puʻupuʻu 7P e pili ana i kahi pūhui mea ola i loaʻa nā ʻātoma kalapona ʻehiku. I loko o ka kemika organik, he mea koʻikoʻi ke kalapona no ka mea hiki iā ia ke hana i nā paʻa paʻa me nā ʻātoma ʻē aʻe, me nā ʻātoma kalapona, e hana i nā molekala paʻakikī. Hiki i kēia mau moleke ke loaʻa i nā ʻano waiwai a me nā hana, e hana ana i nā pūhui kalapona i nā poloka kūkulu o ke ola. I nā ʻano holoholona o ka ʻeha nerve optic, ua hōʻike ʻia ka 7p pūhui e hoʻoulu i ka ulu ʻana o GAP-43-positive axons, e hōʻike ana i ka neurite ulu ʻana o ka hui 7p in vitro e unuhi i ka hoʻoulu ʻana o ka axonal regeneration in vivo. ʻO ka pauka 7P he keʻokeʻo a keʻokeʻo keʻokeʻo i hana ʻia ma ke ʻano he hui tandem no ka ʻike ʻana i nā mea hoʻopiʻi antagonist antagonist thromboxane hana ʻelua. ʻO ka ʻoiaʻiʻo, ua hōʻike ka hui 7p i ke koho no ka prostaglandin I2 synthase (PTGIS, CYP8A1) pili i ka thromboxane synthase (CYP5A1). ʻO ka nootropic compound 7P pauka e hoʻoikaika i ka uluʻana o Gap-43-positive axons, a laila e hoʻoulu ai i ka axonal regeneration i ke kino. Hoʻolālā ʻia ʻo Complex 7p kiʻekiʻe e hoʻomaikaʻi i ka hoʻonohonoho ʻana, hoʻomaikaʻi i ke ʻano a kōkua i ke kaua ʻana i ka luhi. Hoʻopaʻa pū ia i ka oxidation o ka lolo a kōkua i ke kaua ʻana i ka pōʻino o ka lolo ma muli o ka inu ʻana i ka waiʻona.

Hiʻona

结构图

(1) Maʻemaʻe kiʻekiʻe: Hiki i ka Compound 7P ke loaʻa nā huahana maʻemaʻe kiʻekiʻe ma o nā kaʻina hana hoʻomaʻemaʻe. ʻO ka maʻemaʻe kiʻekiʻe, ʻoi aku ka maikaʻi o ka bioavailability a me ka liʻiliʻi o nā hopena ʻino.

(2) Palekana: Ua hōʻoia ʻia ʻo Compound 7P i palekana no ke kino kanaka.

(3) Paʻa: He kūpaʻa maikaʻi ka Compound 7P a hiki ke mālama i kāna hana a me ka hopena ma lalo o nā kaiapuni like ʻole a me nā kūlana mālama.

Nā noi

Hoʻonui ka hui 7p i ka ulu ʻana o ka neurite o nā neurons moʻomeheu i loaʻa mai ka hippocampus, cerebral cortex, a me retina a hoʻoulu i ka hoʻōla hou ʻana o ka optic nerve i nā ʻano holoholona o ka ʻeha nerve optic. Hoʻonui ia i ka hoʻohui ʻana, mālama i ka pōʻino o ka lolo e pili ana i ka waiʻona, a pale i ka oxidation a puni ka lolo. He kōkua nō hoʻi i ka hoʻomaikaʻi ʻana i ke ʻano a me ka hakakā ʻana i ka luhi.


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