1,4-DihydronicotinaMide Riboside pauka mea hana CAS No.:19132-12-8 98% maemae min. no nā mea hoʻohui
Nā Kūlana Huahana
inoa huahana | 1,4-DihydronicotinaMide Riboside |
inoa ʻē aʻe | 1,4-DIHYDRONICOTINAMIDE RIBOSIDE1-[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,4-dihydropyridine-3-carboxamideSCHEMBL188493711-[(3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-4H-PYRIDINE-3-CARBOXAMIDE |
CAS No. | 19132-12-8 |
ʻAno molekala | C11H16N2O5 |
Kaumaha molekula | 256.26 |
Maemae | 98% |
Ka nana aku | Pauda keʻokeʻo |
Hoʻopili | 1kg / ʻeke; 25kg / pahu |
Palapala noi | Pākuʻi ʻai meaʻai maka |
Hoʻolauna huahana
1,4-dihydronicotinamide riboside, i ʻike ʻia ʻo NRH.ʻO ke ʻano hoʻohaʻahaʻa o NRH he potent NAD + precursor e kōkua i ka hoʻopiha ʻana i kāna mau pae i loko o ke kelepona.
ʻO ka mea mua a me ka mea nui, he mea nui e hoʻomaopopo i ke kuleana o NAD + i ke kino. ʻO NAD + kahi coenzyme e pili ana i nā kaʻina cellular he nui, me ka metabolism ikehu, hoʻoponopono DNA, a me ka hōʻike ʻana. I ko mākou mau makahiki, ua emi ko mākou pae o NAD +, i hoʻopili ʻia i ke kaʻina hana ʻelemakule a me nā maʻi pili i ka makahiki. Ua alakaʻi kēia i ka makemake nui i ka ʻike ʻana i nā molekole e hiki ke hoʻonui i nā pae NAD + i ke kino, a ʻo 1,4-dihydronicotinamide riboside kekahi o ia mole.
ʻO 1,4-dihydronicotinamide riboside kahi mea hoʻomaka mua NAD +, a ua hōʻike ka noiʻi hiki iā ia ke hoʻonui i nā pae NAD + i nā cell. Ua alakaʻi kēia i ka noʻonoʻo ʻana e hiki i ka 1,4-dihydronicotinamide riboside supplementation ke loaʻa i ka hiki ke therapeutic i kahi ākea o nā kūlana olakino, me nā maʻi metabolic, nā maʻi neurodegenerative, a me ka emi ʻana o ka ʻelemakule.
I ka ʻoiaʻiʻo, aia nā hōʻike e hōʻike ana he ʻoi aku ka maikaʻi o ka 1,4-dihydronicotinamide riboside ma mua o kona mole makua, nicotinamide riboside, i ka hoʻonui ʻana i nā pae NAD +. ʻO kēia no ka mea ʻo 1,4-dihydronicotinamide riboside kahi mea hoʻemi ikaika, ʻoi aku ka maikaʻi o ka hāʻawi ʻana i nā electrons i ke ala synthesis NAD +. ʻO ka hopena, loaʻa iā ia ka hiki ke hoʻonui i ka hana ʻana i ka cellular NAD +.
Ma kahi o kāna kuleana ma NAD + biosynthesis, loaʻa pū kekahi mau waiwai antioxidant 1,4-dihydronicotinamide riboside. ʻO ke koʻikoʻi oxidative, ka hopena ma muli o ke kaulike ʻole ma waena o nā radical manuahi a me nā antioxidants i loko o ke kino, pili i nā maʻi he nui, e like me ka maʻi kanesa, ka maʻi cardiovascular, a me nā maʻi neurodegenerative. Ma ka hōʻemi ʻana i nā radical manuahi a me ka hōʻemi ʻana i ka pōʻino oxidative, hiki i ka 1,4-dihydronicotinamide riboside ke hāʻawi i nā pono olakino hou aʻe ma mua o kāna kuleana ma ke ʻano he NAD + precursor.
Hiʻona
(1) Maʻemaʻe kiʻekiʻe: 1,4-dihydronicotinamide riboside hiki ke loaʻa i nā huahana maʻemaʻe kiʻekiʻe ma o nā kaʻina hana hoʻomaʻemaʻe. ʻO ka maʻemaʻe kiʻekiʻe, ʻoi aku ka maikaʻi o ka bioavailability a me ka liʻiliʻi o nā hopena ʻino.
(2) Palekana: 1,4-dihydronicotinamide riboside kahi huahana kūlohelohe i hōʻike ʻia he palekana no ke kino o ke kanaka.
(3) Paʻa: 1,4-dihydronicotinamide riboside he kūpaʻa maikaʻi a hiki ke mālama i kāna hana a me ka hopena ma lalo o nā ʻano like ʻole a me nā kūlana mālama.
Nā noi
ʻO 1,4-Dihydronicotinamide ka ʻano hōʻemi o ka riboside nicotinamide. Hiki iā ia ke noho i loko o nā ʻano oxidized a i hoʻemi ʻia a he precursor ia i ka NAD hou i ʻike ʻia (nicotinamide adenine dinucleotide), i loaʻa ma ke ʻano he mea hoʻohui, me ka NRH ʻoi aku ka ikaika a me ka wikiwiki o ka NAD + precursor ma mua o NR.