ʻO ka ʻepekema ma hope o ka pauka Palmitoylethanolamide (PEA): ʻO ka mea āu e ʻike ai

ʻO Palmitoylethanolamide  he amide waikawa momona endogenous nona ka papa o nā agonists kumu nuklea. ʻO ia kekahi o nā hui analgesic endogenous koʻikoʻi a me nā anti-inflammatory i hōʻike ʻia he pono ʻaʻole wale i ka ʻeha koʻikoʻi akā i ka ʻeha mau loa. Ma ke ʻano he mea hoʻomaha ʻeha kūlohelohe, he koho maikaʻi ia i nā lāʻau lapaʻau kuʻuna e hiki ke hoʻoulu i nā hopena ʻaoʻao.

Ua hōʻike ʻia ʻo PEA he mau waiwai anti-inflammatory, antinociceptive, neuroprotective, a me anticonvulsant. Ke noiʻi nei ʻo PEA i nā poʻe me nā ʻano ʻeha like ʻole, ka mumū a me nā syndromes ʻeha i nā hoʻokolohua lapaʻau like ʻole. Nā noi: ʻO Palmitoylethanolamide kahi waena synthesis organik a me ka waena lāʻau lapaʻau, hiki ke hoʻohana ʻia i nā kaʻina hana noiʻi a me ka hoʻomohala ʻana i ka hale hana a me nā kaʻina hana noiʻi a me ka hoʻomohala ʻana i nā kemika a me nā lāʻau lapaʻau.

I nā ʻoihana noiʻi ʻepekema a me nā ʻoihana o kēia lā, ʻo Palmitoylethanolamide, ma ke ʻano he mea maka kemika koʻikoʻi, ua loaʻa ka nānā nui ʻia no kona mau waiwai kemika kū hoʻokahi a me nā manaʻolana hoʻohana ākea.

1. Hoʻomākaukau ʻana o Palmitoylethanolamide

ʻO ka hoʻomākaukau ʻana o Palmitoylethanolamide e pili pinepine ana i kahi hopena esterification. I ka wā o ke kaʻina hana hoʻomākaukau, hana ka palmitadecanoic acid a me ka ethanol i kahi hopena esterification ma lalo o ka hana a kahi mea hoʻoulu e hana i ka palmitadecanamide ethanol. I ka wā o ke kaʻina hana hoʻomākaukau, ʻo nā mea e like me ka mahana o ka hopena, ke ʻano o ka mea hoʻoulu a me ka nui, a me ka manawa hopena he hopena koʻikoʻi i ka maikaʻi a me ka hua o ka huahana. No laila, ʻo ka hoʻomaikaʻi ʻana i ke kaʻina hana hoʻomākaukau ke kī i ka hoʻomaikaʻi ʻana i ka maikaʻi o ka huahana a me ka hōʻemi ʻana i nā kumukūʻai.

2. Nā Waiwai o Palmitoylethanolamide

He keʻokeʻo a melemele iki ka Palmitoylethanolamide me ka solubility maikaʻi a me ke kūpaʻa. He paʻa ia i ka mahana o ka lumi, akā hiki ke hoʻoheheʻe ʻia i nā ʻano mea hoʻoheheʻe organik like ʻole ma kahi mahana, e like me ka ethanol, acetone, a pēlā aku. Eia kekahi, loaʻa iā Palmitoylethanolamide ke kūpaʻa wela a me ke kemika maikaʻi, e hiki ai iā ia ke mālama i kona ʻano a me nā waiwai ma lalo o nā mahana kiʻekiʻe a me nā ʻano paʻakikī.

3. Ka hoʻohana ʻana o Palmitoylethanolamide

1. Noiʻi a me ka hoʻomohala ʻana i nā lāʻau lapaʻau a me nā keʻena hoʻokolohua:

●He mea koʻikoʻi ka PEA no nā lāʻau lapaʻau, hoʻohana ʻia i nā kaʻina hana noiʻi a me ka hoʻomohala ʻana i loko o ka hale hana a me nā kaʻina hana noiʻi a me ka hoʻomohala ʻana i nā lāʻau lapaʻau kemika.

●Ua hōʻike ʻia he mau waiwai anti-inflammatory, analgesic, neuroprotective a me anticonvulsant a kūpono hoʻi no ka mālama ʻana i ka ʻeha mau loa, epilepsy, cerebral ischemia a me ka hahau ʻana.

2. ʻOihana hoʻonani:

●Loaʻa iā PEA nā hana o ka surfactant a me ka foam accelerator a hoʻohana ʻia i ka hana ʻana i nā mea hoʻonani e like me nā moisturizers a me nā shampoos.

●Hiki iā ia ke hoʻoikaika i ke kūlike a me ke kūpaʻa o ka huahana, me ka hoʻomaikaʻi ʻana i ka hopena moisturizing a me ka moisturizing o ka huahana.

3. ʻOihana lole:

●Hoʻohana ʻia ka PEA ma ke ʻano he mea palupalu, mea antistatic a me ka lubricant e hoʻomaikaʻi i ka palupalu a me ka ʻōlinolino o nā lole a hoʻemi i ke koina friction a me nā hopena electrostatic.

4. ʻOihana palakiko:

● Ma ke ʻano he plasticizer, lubricant a me ka dispersant, hoʻomaikaʻi ʻo PEA i ka palupalu a me ka paʻakikī o nā plastics a hoʻemi i ka mahana hana a me ka hoʻohana ʻana i ka ikehu.

5. Anti-inflammatory a me analgesic:

●Hoʻemi ka PEA i nā hōʻailona mumū ma ka hoʻololi ʻana i ka hōʻike ʻana o ka gene, loaʻa iā ia nā hopena anti-inflammatory a me analgesic, a kūpono hoʻi no ka mālama ʻana i nā ʻano ʻeha like ʻole a me nā maʻi mumū.

6. Nā noi ʻē aʻe:

●Ma ke kahua o ka ikehu hou, hiki ke hoʻohana ʻia ʻo PEA e hana i nā mea ikehu hou e like me nā cell solar a me nā pila lithium-ion.

● Ma ke kahua o ka palekana o ke kaiapuni, hiki ke hoʻohana ʻia e hana i nā plastik biodegradable, nā uhi aloha kaiapuni a me nā huahana aloha kaiapuni ʻē aʻe.

●Ma ke kahua lāʻau lapaʻau, hiki ke hoʻohana ʻia e hana i nā mea lāʻau lapaʻau e like me nā mea lawe lāʻau a me nā mea hoʻokuʻu mau.

Hōʻike kēia mau hoʻohana i ka noi ākea a me ka waiwai kūpono o ka palmitamide ethanol ma nā ʻoihana he nui.

4. Nā ʻano hoʻomohala e hiki mai ana o Palmitoylethanolamide

Me ka holomua mau o ka ʻepekema a me ka ʻenehana a me ka wikiwiki o ka hoʻomohala ʻana o ka ʻoihana, e hoʻomau ka hoʻonui ʻia ʻana o nā kahua noi o Palmitoylethanolamide. I ka wā e hiki mai ana, e piʻi mālie ka hoʻohana ʻana o Palmitoylethanolamide i ka ikehu hou, ka palekana o ke kaiapuni, ka lāʻau lapaʻau a me nā kahua ʻē aʻe. No ka laʻana, ma ke kahua o ka ikehu hou, hiki ke hoʻohana ʻia ʻo Palmitoylethanolamide e hana i nā mea ikehu hou e like me nā cell solar a me nā pila lithium-ion; ma ke kahua o ka palekana o ke kaiapuni, hiki ke hoʻohana ʻia e hana i nā huahana aloha kaiapuni e like me nā plastics biodegradable a me nā uhi aloha kaiapuni; ma ke kahua o ka lāʻau lapaʻau, hiki ke hoʻohana ʻia Hana ʻana i nā mea lāʻau lapaʻau e like me nā mea lawe lāʻau a me nā mea hoʻokuʻu mau.

Eia kekahi, i ka hoʻomau ʻana o ka ʻike o ka poʻe i ke olakino a me ka palekana o ke kaiapuni e piʻi aʻe ana, e piʻi aʻe ana nā koi maikaʻi a me ka hana no Palmitoylethanolamide. No laila, ʻo ka noiʻi a me ka hoʻomohala ʻana a me ka hana ʻana o Palmitoylethanolamide i ka wā e hiki mai ana e uku nui aku i ka mālama ʻana i ke kaiapuni, ka palekana a me ke kūpaʻa. I ka manawa like, i mea e hoʻokō ai i nā pono o nā ʻano like ʻole, e lilo ka noiʻi a me ka hoʻomohala ʻana o nā derivatives Palmitoylethanolamide hou i kuhikuhi koʻikoʻi i ka wā e hiki mai ana.

He amide momona momona endogenous ka PEA nona ka papa o nā agonists kumu nuklea. Ua hōʻike ʻia ʻo PEA e hoʻopaʻa i nā mea loaʻa i loko o ka nucleus (nā mea loaʻa nuklea) a hoʻokō i nā ʻano hana olaola like ʻole e pili ana i ka ʻeha mau a me ka mumū. Manaʻo ʻia ʻo ka pahuhopu nui ʻo ia ka peroxisome proliferator-activated receptor alpha (PPAR-alpha).　

He mea hana i hoʻopaʻa inoa ʻia ʻo Suzhou Myland Pharm & Nutrition Inc. i hoʻolako i ka pauka Oleoylethanolamide (OEA) kiʻekiʻe a me ka maʻemaʻe.

Ma Suzhou Myland Pharm, ua kūpaʻa mākou i ka hāʻawi ʻana i nā huahana kiʻekiʻe loa ma nā kumukūʻai maikaʻi loa. Ua hoʻāʻo pono ʻia kā mākou pauka Oleoylethanolamide (OEA) no ka maʻemaʻe a me ka ikaika, e hōʻoiaʻiʻo ana e loaʻa iā ʻoe kahi mea hoʻohui kiʻekiʻe hiki iā ʻoe ke hilinaʻi. Inā makemake ʻoe e kākoʻo i ke olakino cellular, hoʻoikaika i kāu ʻōnaehana pale a hoʻomaikaʻi paha i ke olakino holoʻokoʻa, ʻo kā mākou pauka Oleoylethanolamide (OEA) ke koho kūpono loa.

Me 30 mau makahiki o ka ʻike a hoʻokele ʻia e ka ʻenehana kiʻekiʻe a me nā hoʻolālā R&D i hoʻonohonoho pono ʻia, ua hoʻomohala ʻo Suzhou Myland Pharm i nā huahana hoʻokūkū a lilo i ʻoihana hoʻohui ʻepekema ola hou, synthesis maʻamau a me nā lawelawe hana.

Eia kekahi, he mea hana i hoʻopaʻa inoa ʻia ʻo Suzhou Myland Pharm i ka FDA. He hou a he multifunctional nā kumuwaiwai R&D o ka hui, nā hale hana, a me nā mea hana loiloi, a hiki ke hana i nā kemika mai milligrams a i tons ma ke anakahi, a kūlike me nā kūlana ISO 9001 a me nā kikoʻī hana GMP.