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ʻO ka ʻepekema ma hope o ka pauka Palmitoylethanolamide (PEA): He aha kāu e ʻike ai

ʻO Palmitoylethanolamide  ʻO ia ka endogenous fatty acid amide e pili ana i ka papa o ka nuclear factor agonists. ʻO ia kekahi o nā mea analgesic endogenous koʻikoʻi a me nā pūhui anti-inflammatory i hōʻike ʻia i ka maikaʻi ʻaʻole wale i ka ʻeha a me ka ʻeha mau. Ma keʻano he mea hōʻehaʻeha maoli, he mea maikaʻi ia i nā lāʻau lapaʻau maʻamau i hiki ke hoʻoulu i nā hopena.

Ua hōʻike ʻia ka PEA i nā waiwai anti-inflammatory, antinociceptive, neuroprotective, a me nā anticonvulsant. Ke ʻimi nei ʻo PEA i nā poʻe me nā ʻano ʻeha like ʻole, nā ʻeha a me nā maʻi ʻeha i nā hoʻokolohua lapaʻau like ʻole. Nā noi: ʻO Palmitoylethanolamide kahi mea hoʻohuihui kūlohelohe a me ka lāʻau lapaʻau waena, hiki ke hoʻohana ʻia i ka noiʻi noiʻi a me nā kaʻina hana hoʻomohala a me nā kaʻina hana noiʻi a me nā lāʻau lapaʻau.

I kēia mau lā noiʻi ʻepekema a me nā ʻoihana ʻenehana, ʻo Palmitoylethanolamide, ma ke ʻano he mea koʻikoʻi koʻikoʻi kemika, ua loaʻa ka manaʻo nui no kāna mau waiwai kemika kūʻokoʻa a me nā manaʻo noiʻi ākea.

1. Ka hoomakaukau ana o Palmitoylethanolamide

ʻO ka hoʻomākaukau ʻana o Palmitoylethanolamide ka mea maʻamau i ka hopena esterification. I ka wā o ka hoʻomākaukau ʻana, loaʻa ka palmitadecanoic acid a me ka ethanol i kahi hopena esterification ma lalo o ka hana a kahi catalyst e hoʻohua i ka ethanol palmitadecanamide. I ka wā o ka hoʻomākaukau ʻana, he hopena koʻikoʻi ko nā mea e like me ka wela o ka hopena, ke ʻano catalyst a me ka dosage, a me ka manawa pane i ka maikaʻi a me ka hua o ka huahana. No laila, ʻo ka hoʻomaikaʻi ʻana i ke kaʻina hana hoʻomākaukau ke kī i ka hoʻomaikaʻi ʻana i ka maikaʻi o ka huahana a me ka hōʻemi ʻana i nā kumukūʻai.

ʻO Palmitoylethanolamide

2. Na waiwai o Palmitoylethanolamide

ʻO ka Palmitoylethanolamide kahi paʻa keʻokeʻo a melemele iki me ka solubility maikaʻi a me ka paʻa. He paʻa i ka lumi wela, akā hiki ke hoʻoheheʻe ʻia i nā ʻano mea hoʻoheheʻe kūlohelohe i kekahi mahana, e like me ka ethanol, acetone, a me nā mea ʻē aʻe. nā wela kiʻekiʻe a me nā kaiapuni paʻakikī.

3. Hoʻohana i ka Palmitoylethanolamide

1. ʻO ka noiʻi a me ka hoʻomohala ʻana i ka lāʻau lapaʻau a me ka hale hana.

●PEA mea koʻikoʻi pharmaceutical intermediate, i hoʻohana 'ia i loko o ke keʻena noiʻi a me ka hoʻomohala kaʻina hana a me kemika lāʻau noiʻi a me ka ulu ana kaʻina hana.

● Ua hōʻike ʻia he anti-inflammatory, analgesic, neuroprotective a me anticonvulsant waiwai a kūpono no ka mālama ʻana i ka ʻeha mau, epilepsy, cerebral ischemia a me ka hahau.

2. ʻoihana mea hoʻonani:

●PEA nā hana o ka surfactant a me ka hoʻohūhū accelerator a hoʻohana ʻia i ka hana ʻana i nā mea hoʻonaninani e like me nā moisturizers a me nā shampoos.

● Hiki iā ia ke hoʻonui i ka paʻa a me ka paʻa o ka huahana, me ka hoʻomaikaʻi ʻana i ka moisturizing a me ka moisturizing hopena o ka huahana.

3. Hana lole lole:

● Hoʻohana ʻia ka PEA ma ke ʻano he mea palupalu, antistatic agent a me ka lubricant e hoʻomaikaʻi i ka palupalu a me ka nani o nā lole a hoʻemi i ka hopena friction a me nā hopena electrostatic.

4. ʻoihana palaki:

●Ma ke ʻano he plasticizer, lubricant a me ka dispersant, hoʻomaikaʻi ʻo PEA i ka palupalu a me ka paʻakikī o nā plastics a hoʻemi i ka mahana hana a me ka hoʻohana ʻana i ka ikehu.

5. Anti-inflammatory a me analgesic:

● Hoʻemi ka PEA i nā hōʻailona maʻi ma o ka hoʻololi ʻana i ka hōʻike gene, loaʻa nā hopena anti-inflammatory a me analgesic, a kūpono no ka mālama ʻana i nā ʻano ʻeha like ʻole a me nā maʻi ʻeha.

6. Nā mea hoʻohana ʻē aʻe:

●Ma ke kahua o ka ikehu hou, hiki ke hoʻohana ʻia ka PEA no ka hana ʻana i nā mea ikehu hou e like me nā pūnaewele lā a me nā pā lithium-ion.

●Ma ke kahua o ka mālama ʻana i ke kaiapuni, hiki ke hoʻohana ʻia no ka hana ʻana i nā plastic biodegradable, nā mea hoʻonaninani kūlohelohe a me nā huahana ʻē aʻe.

●Ma ke kahua lāʻau lapaʻau, hiki ke hoʻohana ʻia e hana i nā mea lāʻau lapaʻau e like me nā mea lawe lāʻau a me nā mea hoʻokuʻu hoʻomau.

Hōʻike kēia mau hoʻohana i ka noi ākea a me ka waiwai kūpono o ka palmitamide ethanol i nā ʻoihana he nui.

4. Nā ʻano hoʻomohala e hiki mai ana o Palmitoylethanolamide

Me ka hoʻomau mau ʻana o ka ʻepekema a me ka ʻenehana a me ka hoʻomohala wikiwiki ʻana o ka ʻoihana, e hoʻomau ka hoʻonui ʻana i nā kahua noi o Palmitoylethanolamide. I ka wā e hiki mai ana, e piʻi mālie ka hoʻohana ʻana o Palmitoylethanolamide i ka ikehu hou, ka mālama ʻana i ke kaiapuni, ka lāʻau lapaʻau a me nā māla ʻē aʻe. No ka laʻana, ma ke kahua o ka ikehu hou, hiki ke hoʻohana ʻia ʻo Palmitoylethanolamide e hana i nā mea ikehu hou e like me nā cell solar a me nā pā lithium-ion; ma ke kahua o ka mālama ʻana i ke kaiapuni, hiki ke hoʻohana ʻia no ka hana ʻana i nā huahana kūlohelohe e like me nā plastic biodegradable a me nā uhi hoʻonaninani; ma ke kahua o ka lāʻau lapaʻau, hiki ke hoʻohana ʻia i ka hana ʻana i nā mea lāʻau lapaʻau e like me nā mea lawe lāʻau a me nā mea hoʻokuʻu hoʻomau.

Eia kekahi, ke hoʻomau nei ka ʻike o ka poʻe i ke olakino a me ka palekana o ke kaiapuni, e piʻi a kiʻekiʻe hoʻi ka maikaʻi a me nā koi o ka hana no Palmitoylethanolamide. No laila, ʻo ka noiʻi e hiki mai ana a me ka hoʻomohala ʻana a me ka hana ʻana o Palmitoylethanolamide e uku nui aku i ka mālama ʻana i ke kaiapuni, palekana a me ka hoʻomau. I ka manawa like, i mea e hoʻokō ai i nā pono o nā ʻano like ʻole, e lilo ka noiʻi a me ka hoʻomohala ʻana o nā derivatives Palmitoylethanolamide hou i mea koʻikoʻi i ka wā e hiki mai ana.

ʻO ka PEA kahi amide fatty acid endogenous e pili ana i ka papa o ka nuclear factor agonists. Ua hōʻike ʻia ka PEA e hoʻopaʻa i nā mea loaʻa i loko o ka nucleus (nuclear receptors) a hoʻoikaika i nā ʻano hana olaola nui e pili ana i ka ʻeha mau a me ka mumū. ʻO ka pahuhopu nui i manaʻo ʻia he peroxisome proliferator-activated receptor alpha (PPAR-alpha). 

ʻO Suzhou Myland Pharm & Nutrition Inc. he mea hana i kākau inoa ʻia e FDA e hāʻawi ana i ka pauka Oleoylethanolamide (OEA) kiʻekiʻe a maikaʻi loa.

Ma Suzhou Myland Pharm mākou e hoʻolako i nā huahana kiʻekiʻe loa i nā kumukūʻai maikaʻi loa. ʻO kā mākou Oleoylethanolamide (OEA) pauka i ho'āʻo ikaikaʻia no ka maʻemaʻe a me ka ikaika, e hōʻoiaʻiʻo ana e loaʻa iāʻoe kahi mea hoʻopihapiha kiʻekiʻe āu e hilinaʻi ai. Inā makemake ʻoe e kākoʻo i ke olakino cellular, hoʻonui i kāu ʻōnaehana pale a hoʻomaikaʻi i ke olakino holoʻokoʻa, ʻo kā mākou Oleoylethanolamide (OEA) pauka ke koho kūpono loa.

Me 30 mau makahiki o ka ʻike a alakaʻi ʻia e ka ʻenehana kiʻekiʻe a me nā hoʻolālā R&D maikaʻi loa, ua hoʻomohala ʻo Suzhou Myland Pharm i nā ʻano huahana hoʻokūkū a lilo i mea hoʻohui ʻepekema ola hou, synthesis maʻamau a me nā ʻoihana lawelawe hana.

Eia kekahi, ʻo Suzhou Myland Pharm kekahi mea hana inoa FDA. ʻO nā kumuwaiwai R&D o ka hui, nā lako hana, a me nā mea hana analytical he mea hou a multifunctional, a hiki ke hana i nā kemika mai ka milligrams a hiki i nā tona i ka unahi, a hoʻokō i nā kūlana ISO 9001 a me nā kikoʻī hana GMP.

Hoʻopau: No ka ʻike maʻamau wale nō kēia ʻatikala a ʻaʻole pono e manaʻo ʻia he ʻōlelo aʻoaʻo olakino. Loaʻa mai kekahi o ka ʻike moʻomanaʻo blog mai ka Pūnaewele a ʻaʻole ʻoihana. ʻO kēia pūnaewele wale nō ke kuleana no ka hoʻokaʻawale ʻana, ka hoʻopili ʻana a me ka hoʻoponopono ʻana i nā ʻatikala. ʻO ke kumu o ka hāʻawi ʻana i nā ʻike hou aʻe ʻaʻole ia he manaʻo ʻae ʻoe i kāna mau manaʻo a hōʻoia paha i ka ʻoiaʻiʻo o kāna ʻike. E nīnau mau i kahi ʻoihana mālama ola ma mua o ka hoʻohana ʻana i nā mea hoʻohui a i ʻole ka hoʻololi ʻana i kāu ʻano mālama ola kino.


Ka manawa hoʻouna: Sep-27-2024