ʻO Urolithin A kahi moleke hoihoi i ke kahua o ka noiʻi anti aging. ʻO kona hiki ke hoʻihoʻi i ka hana kelepona a hoʻomaikaʻi i ke olakino ua hoʻohiki ʻia i nā haʻawina holoholona. Eia naʻe, pono ka noiʻi hou aʻe e hoʻoholo ai i kona pono i loko o nā kānaka. ʻOiai ʻaʻole paha mākou i ʻike i ka punawai o ka ʻōpio, ʻo Urolithin A ke hoʻokokoke nei iā mākou i ka hoʻomaopopo ʻana i nā mea huna o ka ʻelemakule a me ka wehe ʻana i ke kī i kahi ola ʻoi aku ka maikaʻi.
ʻO Urolithin A kahi hui kūlohelohe i loaʻa i ka nānā nui ʻana i nā makahiki i hala iho nei ma muli o kāna mau pono olakino. Ke hōʻike mai nei nā noiʻi e puka mai ana he mau waiwai anti-inflammatory, anti-cancer a me nā mea ʻelemakule.
●ʻO Urolithin A he metabolite i hana ʻia e ka haki ʻana o nā ellagitannins, kahi pūhui polyphenolic i loaʻa i kekahi mau huaʻai a me nā nati. ʻO ka hoʻololi ʻana o nā ellagitannins i ka urolithin A e hana nui ʻia i loko o ka ʻōpū ma muli o ka hana a kekahi mau hua bacteria.
●ʻO ka pomegranate kekahi o nā kumu waiwai nui o nā ellagitannins a no laila ʻo urolithin A. ʻO nā ʻulaʻula ʻulaʻula a i ʻole nā anoano, o nā pomegerane he mau kiʻekiʻe o nā ellagitannins, i hoʻololi ʻia i urolithin A i ka wā o ka ʻai ʻana. ʻO ka wai pomegranate a me nā ʻāpana he kumu maikaʻi nō hoʻi o ka urolithin A.
●ʻO kekahi hua i loaʻa i ka urolithin A he raspberries. E like me nā pomegerane, ua waiwai nā raspberries i nā ellagitannins, ʻoi loa i kā lākou mau hua. ʻO ka ʻai mau ʻana i nā raspberry hou a i ʻole ka hau hau e hoʻonui i ka pae urolithin A i ke kino.
●ʻO kekahi mau huaʻai, e like me ka walnuts a me ka pistachios, loaʻa pū kekahi i ka nui o ka urolithin A. ʻOiai ua loaʻa ka urolithin A i nā haʻahaʻa haʻahaʻa i hoʻohālikelike ʻia me nā huaʻai e like me nā pomegerane, me kēia mau huaʻai i kāu meaʻai hiki ke kōkua i ka hoʻonui ʻana i kāu ʻai nui o ka urolithin A.
ʻOiai ʻo nā huaʻai hou a me nā nati he kumu meaʻai maikaʻi loa ia o ka urolithin A, pono e haʻi ʻia aia nō nā mea hoʻohui urolithin A. Hiki i kēia mau mea hoʻopihapiha ke hāʻawi i kahi ala kūpono e hoʻonui ai i kāu urolithin A intake.
ʻO Urolithin A kahi mea i loaʻa mai kahi mea maoli i kapa ʻia ʻo ellagitannin, i loaʻa i loko o kekahi mau hua e like me nā pomegerane a me nā hua. Ke ʻai mākou i kēia mau huaʻai, hoʻohiolo kā mākou ʻōpū i nā ellagitannins i urolithin A, e ʻae i ko mākou kino e pōmaikaʻi mai kēia pūhui kupaianaha.
ʻO kekahi o nā mea hoihoi loa e pili ana i ka urolithin A ʻo kona hiki ke hoʻōla hou i ka mitochondria, nā hale mana o kā mākou mau cell. I ko mākou mau makahiki, e emi ana ko mākou mitochondria, e alakaʻi ana i ka emi ʻana o ka ikehu cellular. Ua hōʻike ka noiʻi e hiki i ka urolithin A ke hoʻoikaika i kahi kaʻina i kapa ʻia ʻo mitophagy, kahi e hoʻomaʻemaʻe ai i ka mitochondria dysfunctional a hoʻoulu i ka hana o nā mea olakino hou. Ke alakaʻi nei kēia kaʻina hana i ka hoʻomaikaʻi ʻana i ka hana ikehu a me ka hana kelepona holoʻokoʻa.
Eia kekahi, ua ʻike ʻia ka urolithin A e hoʻonui i ke olakino a me ka ikaika. I ko mākou mau makahiki, maʻa mākou e nalowale i ka nui o ka ʻiʻo, e alakaʻi ana i ka nāwaliwali a me ka emi ʻana o ka neʻe. Eia naʻe, ua hōʻike ʻia nā haʻawina i nā holoholona kahiko i ka hoʻonui ʻana me ka urolithin A e hoʻoikaika i ka ulu ʻana o ka ʻiʻo a pale i ka pau ʻana o ka ʻiʻo.
ʻO kekahi pōmaikaʻi ʻē aʻe o Urolithin A ʻo kona pale ʻana i nā maʻi neurodegenerative e like me Alzheimer a me Parkinson. Hōʻike ʻia kēia mau maʻi e ka hōʻiliʻili ʻana o nā protein ʻona i loko o ka lolo, e alakaʻi ana i ka emi ʻana o ka cognitive a me nā pilikia neʻe. Ua hōʻike ʻia nā haʻawina hou e hiki i ka urolithin A ke kōkua i ka wehe ʻana i kēia mau protein ʻino, e hōʻemi ana i ka pilikia a me ka holomua o kēia mau maʻi neurodegenerative.
1. E ʻai i nā meaʻai momona i nā ellagitannins: No ka hoʻonui maoli ʻana i nā pae urolithin, ʻo ka ʻai ʻana i nā meaʻai momona i nā ellagitannins ke kī. ʻO nā pomegerane, nā strawberries, nā raspberries, a me nā ʻeleʻele he kumu maikaʻi loa ia o nā ellagitannins. ʻO ka hoʻokomo ʻana i kēia mau huaʻai i kāu meaʻai hiki ke hoʻonui i ka hana urolithin i kou ʻōpū.
2. ʻO ka hoʻomaikaʻi ʻana i ke olakino Gut: He mea koʻikoʻi ka loaʻa ʻana o kahi microbiota ʻōpū olakino no ka hana urolithin. No ke kākoʻo ʻana i kahi microbiome ʻōpū ʻokoʻa a kaulike, e hoʻokomo i nā meaʻai fermented e like me ka yogurt, kefir, sauerkraut, a me kimchi i kāu ʻai. Hoʻokomo kēia mau meaʻai i ka bacteria maikaʻi i kou ʻōpū, e hoʻonui ai i ka hana urolithin.
3. E lawe i nā mea hoʻohui urolithin: Ma kahi o nā kumu meaʻai, loaʻa pū nā mea hoʻohui urolithin ma ka mākeke. Hāʻawi kēia mau mea hoʻopihapiha i nā urolithins koʻikoʻi, he mea pono paha ia no ka poʻe paʻakikī i ka ʻai ʻana i nā meaʻai waiwai nui o ka ellagitannin i kēlā me kēia manawa a i ʻole nā pilikia olakino.
4. Hoʻohui i nā ellagitannins me nā kumu momona: ʻoi aku ka maʻalahi o ka ellagitannins i ke kino ke ʻai ʻia me nā kumu momona maikaʻi. E noʻonoʻo e hoʻohui i kekahi mau nati, nā hua, a i ʻole ka aila ʻoliva liʻiliʻi i ka hua e hoʻonui ai i ka absorption o nā ellagitannins a hoʻonui i ka hana urolithin.
He ʻokoʻa ka manawa e hana ai ka urolithin A me kekahi mau kumu. ʻO ka mea nui loa ka metabolism pilikino. ʻOkoʻa ka hana ʻana o ke kino o kēlā me kēia kanaka, e pili pū ana i ka wikiwiki o ke kino a hoʻohana i ka urolithin A. Eia kekahi, ʻo ke ʻano a me ke ʻano i hoʻopau ʻia ai ka urolithin A hiki ke hoʻopili i ka manawa o ka hoʻomaka ʻana o ka hana.
Ua hōʻike nā haʻawina i ka ʻai ʻana i nā ʻano kūlohelohe o urolithin A, e like me ka wai pomegerane a i ʻole kekahi mau hua, hiki ke hana i nā pae ʻike ʻia o ka pūhui i loko o ke koko i loko o nā hola. Eia naʻe, ʻaʻole hiki ke ʻike koke ʻia nā hopena o ka urolithin A, no ka mea, ʻoi aku ka nānā ʻana o nā hana o ka hui i nā pono olakino lōʻihi.
He mea nui e hoʻomaopopo i ka urolithin A ʻaʻole ia he hoʻoponopono wikiwiki no kekahi kūlana olakino. Akā, manaʻo ʻia e hoʻokō i kāna mau hopena ma o ka hoʻāla ʻana i kahi kaʻina hana hou o ke kino i kapa ʻia ʻo autophagy. ʻO kēia kaʻina hana ka wāwahi ʻana a me ka wehe ʻana i nā cell a me nā protein i pōʻino, hiki ke loaʻa nā hopena lōʻihi i ke olakino a me ka maikaʻi. Ke hoʻomau nei ka noiʻi e pili ana i ka lōʻihi e ʻike ai i nā pono kūpono o ka urolithin A.
ʻO ka noiʻi e pili ana i nā hopena ʻaoʻao o ka urolithin A ʻaʻole i kaupalena ʻia, no ka mea, he kahua noiʻi hou ia. ʻO ka hapa nui o nā haʻawina i hana ʻia a hiki i kēia lā ua kālele i kāna mau hopena maikaʻi ma mua o nā hopena ʻino. Eia nō naʻe, he mea koʻikoʻi e hoʻomau me ka akahele a hoʻomaopopo i nā pilikia e hiki mai ana.
ʻO kahi pilikia me ka hoʻohana ʻana i ka urolithin A ʻo ia ke launa pū me kekahi mau lāʻau. Ma ke ʻano he meaʻai meaʻai, hiki ke launa pū me nā lāʻau lapaʻau i hoʻololi ʻia e nā enzymes ate like. Hiki ke hoʻololi i ka maikaʻi a palekana paha o kēia mau lāʻau. No laila, he mea nui e kamaʻilio i kahi kauka mālama ola ma mua o ka lawe ʻana i ka urolithin A inā ʻoe e lawe i nā lāʻau lapaʻau ʻē aʻe.
ʻO kekahi hiʻohiʻona e noʻonoʻo ʻia ʻo ia ke ʻano o ka urolithin A. I kēia manawa, ʻaʻohe mea i ʻōlelo ʻia i kēlā me kēia lā a i ʻole nā kuhikuhi kuhikuhi kikoʻī no kēia pūhui. No laila, paʻakikī ke hoʻoholo inā loaʻa kahi maʻi maikaʻi loa, a i ʻole he mau hopena ʻaoʻao e pili ana me nā kau kiʻekiʻe. Manaʻo ʻia e hahai i nā kuhikuhi ma ka lepili huahana a i ʻole e nīnau i kahi mea mālama olakino e hoʻoholo ai i ke ʻano kūpono.
Ka manawa hoʻouna: Iune-21-2023
