ʻO 6-paradol kahi hui i loaʻa i loko o ka ʻala. He pūhui kūlohelohe ia i hōʻike ʻia i loaʻa nā pono olakino. E uhi kēia pou i nā mea āpau e pono ai ʻoe e ʻike e pili ana i ka 6-paradol a pehea e pōmaikaʻi ai kou olakino.
- ʻO 6-paradol ka mea ʻono ikaika o nā hua o ka pepa Guinea (Aframomum melegueta a i ʻole nā palapala o ka paradaiso). Loaʻa ia mai kahi papa o nā kemika i kapa ʻia ʻo alkylphenols, ʻo ia nā pūhui kūlohelohe. ʻO 6-paradol, i hana mau ʻia mai ka 6-gingerol ma o ka 6-gingerenol, he mea liʻiliʻi ia o ka ginger, a ma ke ʻano he phenol hoʻoikaika i loaʻa i ka ʻohana ginger, loaʻa ia i loko o nā mea kanu he nui, e like me ka ginger, ka pepa ʻeleʻele a me ka sesame. he laulā o nā hana olaola. ʻO kēia pūhui bioactive ke kumu o ka ʻono ʻono kūʻokoʻa o ka ginger a ua hōʻike ʻia he nui nā pono olakino. Ke hoʻopaʻa ʻia ʻo 6-Paradol i ka pūnaewele ikaika o cyclooxygenase (COX-2), hiki ke pale i ka ulu ʻana o ka maʻi maʻi i nā ʻiole me ka maʻi maʻi ʻili. He nui nā pono olakino e 6-Paradol e like me ka anti-inflammatory, antioxidant, anti-obesity, haʻahaʻa i ke koko a me ka hoʻomaikaʻi ʻana i ka hoʻomanaʻo.
Ua noiʻi ʻia ka hopena o ka 6-paradol i ka lawe ʻana i ka glucose i loko o C2C12 myotubes (mau ʻiʻo ʻiʻo) a me 3T3-L1 adipocytes (nā momona momona). Ua hōʻike nā hopena i ka 6-paradol ʻaʻole i hoʻonui wale i ka lawe ʻana i ka glucose i loko o nā cell ʻelua, akā ua hoʻonui pū i ka hana o kekahi mau protein e hāpai i ka lawe ʻana i ka glucose. Ua ʻike pū ʻia nā hana kikoʻī e hoʻoikaika ai ʻo 6-paradol i ka hoʻohana ʻana i ka glucose. ʻO ka mea mua, hoʻonui ka 6-paradol i ka hana o kahi protein i kapa ʻia ʻo AMPK. ʻO kēia protein ke kuleana no ka hoʻoponopono ʻana i ka ikehu i loko o nā cell, a ma ka hoʻoulu ʻana i ka AMPK, hoʻonui ka 6-paradol i ka lawe ʻana i ka glucose. Ua ʻike ʻia nā haʻawina pili i ka 6-paradol ma ke ʻano he hopena therapeutic kūpono no ka mālama ʻana i ka maʻi diabetes a me ka momona.
No laila, 6-paradol, ma ke ʻano he hui kūlohelohe, hiki ke hoʻohana ʻia i kēlā mau wahi a pau!
(1) Hoʻohana ʻia ma ke ʻano he meaʻai
ʻO 6-Paradol kahi ketone ʻala ʻono ke kumu o ka ʻono a me ka ʻala kū hoʻokahi o Grains of Paradise. Ua hoʻohana ʻia i ka lāʻau lapaʻau kuʻuna no nā kenekulia a hiki ke hoʻohana ʻia i mea ʻala i ka kuke ʻana a me ka mea ʻono i nā mea inu. Loaʻa ia i loko o ka ʻala, ka pepa ʻeleʻele a me nā kumulāʻau sesame, a he sub-organism pū kekahi o ka ginger, a laila hiki ke hoʻohana ʻia i mea hoʻohui i ka meaʻai, kahi hoʻohui maikaʻi loa i ka papa inoa o nā mea ʻala e hiki ke kōkua i ka hoʻonui ʻana i ka ʻono a me ka ʻono. . ʻOiaʻiʻo, hiki ke hoʻohui ʻia ʻaʻole wale i ka meaʻai, akā i nā mea inu. Ke hoʻohālikelike ʻia me nā mea hoʻohui ʻono ʻē aʻe i ka mākeke, he kūlohelohe ʻo 6-parado, no laila ʻo ia ke koho maikaʻi loa e hoʻohui i ka ikaika a me ka ʻono i ka meaʻai a me nā mea inu.
(2) Hiki ke kōkua i ka hoʻomaikaʻi ʻana i ka ʻai
I ke ola, ʻeha ka hapa nui o ka poʻe i ka constipation a me ka ʻeha o ka ʻōpū, no laila hiki iā ʻoe ke noʻonoʻo i ka 6-Paradol, ʻo kekahi o kāna mau hopena ke kōkua i ka wāwahi ʻana a me ka ʻeli ʻana i ka meaʻai i loko o ka ʻōpū, a ke lawe pū ʻia e like me ka meaʻai meaʻai hiki ke hōʻemi i nā pilikia digestive. akā naʻe, ʻaʻole kēia mau pilikia wale nō ka constipation a me ka bloating e like me ka mea i ʻōlelo ʻia ma ka ʻatikala, no ka mea, he mau mea anti-inflammatory ka 6-Paradol, hiki ke kōkua i ka hoʻēmi ʻana i ke kino, hiki ke alakaʻi i ka loaʻa ʻana o ke kaumaha a me nā pilikia olakino ʻē aʻe, e like me ka bloating a nausea.
(3) Hiki ke hoʻomaikaʻi i ka ʻike
ʻO kekahi pōmaikaʻi o 6-paradol, ʻo ia ka mea hiki ke hoʻomaikaʻi i ka hana cognitive. Ua hōʻike nā haʻawina e hiki ke kōkua ʻo 6-Paradol i ka hoʻonui ʻana i ka hoʻomanaʻo a me ka nānā ʻana a pale i ka emi ʻana o ka cognitive pili i ka makahiki. Kōkua ʻo 6-Paradol i ka pale ʻana i nā cell lolo mai ka mumū a me nā antioxidants. Kōkua kēia i ka hoʻomaikaʻi ʻana i ke olakino a me ka hana lōʻihi. Ua hōʻike pū ʻia kāna mea hoʻoikaika ikaika, 6-gingerol, e hoʻoikaika i ke olakino o ke kino.
Ua hōʻike nā haʻawina ʻepekema he nui nā hopena maikaʻi o 6-Paradol i ke kino. Aia kēia mau hopena:
(1) Anti-inflammatory
Loaʻa i ka 6-Paradol nā waiwai anti-inflammatory ikaika i ka mālama ʻana i ka mumū i loko o ke kino. Ua hōʻike nā haʻawina e hiki ke kāohi i ka hana ʻana o nā cytokines pro-inflammatory, nona ke kuleana no ka hoʻomohala ʻana i ka maʻi ʻeha mau.
(2) Nā hopena anti-cancer
Wahi a nā haʻawina, hiki i ka 6-Paradol ke kāohi i ka ulu ʻana o nā maʻi kanesa i loko o ke kino. Ke hana nei kēia pūhui ma ka hoʻoulu ʻana i ka apoptosis, ke kaʻina hana e alakaʻi ai i ka make o nā maʻi maʻi maʻi.
(3) Ka hopena neuroprotective
Kōkua ʻo Neuroprotection i ka pale ʻana i ka ʻōnaehana nerve o kekahi mai ka hōʻeha a i ʻole nā hana pōʻino i hoʻokumu ʻia e nā kūlana olakino me nā hopena neurological ʻino. Loaʻa iā 6-Paradol nā waiwai neuroprotective e kōkua i ka pale ʻana i ka pōʻino o ke aʻalolo a hoʻolohi i ka degeneration o ka ʻōnaehana nerve waena, hiki ke pale i nā maʻi neurological e like me ka maʻi o Alzheimer.
(4) Ka hopena antioxidant
Loaʻa iā 6-Paradol nā waiwai antioxidant ikaika e kōkua i ka hōʻemi ʻana i ka pōʻino oxidative i ke kino. Hiki i kēia pūhui bioactive ke pale i nā ʻano maʻi a me nā kūlana.
ʻAʻohe mea no kekahi, ʻaʻohe ala ʻē aʻe e lilo ai ke kaumaha ma mua o ka hoʻoikaika kino a me ka ʻai ʻana. Ma muli o kēia manaʻo, inā makemake ʻoe e lilo i ke kaumaha, pono ʻoe e hoʻomalu pono i ka helu o nā calorie āu e ʻai ai a hoʻomaʻamaʻa hoʻi e hoʻemi i ka helu o nā calorie pono ʻole, akā ʻaʻole maopopo loa nā hopena. Ua hōʻike ʻia nā haʻawina ʻo kekahi o nā pono nui o 6-Paradol kona hiki ke kōkua i ka hōʻemi ʻana i ke kaumaha, a hiki i ka 6-Paradol ke kōkua i ka pohō kaumaha ma o ka hoʻonui ʻana i ka ikehu i loko o ke kino. Wahi a ka noiʻi, hiki i kēia pūhui bioactive ke hoʻonui i ka mahana o ke kino a me ka wikiwiki o ka metabolism, hiki ke alakaʻi i ka momona momona. Hiki i kēia kaʻina hana ke hoʻoikaika i ka metabolism a puhi i nā calorie hou aʻe, ʻoiai i ka hoʻomaha. ʻO ia hoʻi, me kāna hoʻohana ʻana, ʻaʻole pono ʻoe e hopohopo e pili ana i ka hoʻoikaika kino a me ka ʻai. Hiki iā ʻoe ke hoʻemi iki i ka mea āu e ʻai ai a me ka nui o kāu hoʻomaʻamaʻa ʻana, akā e hoʻonui mau i nā hopena o ke kaumaha.
Mālama ke kino i ka momona o ke kino i ʻelua kala a me nā ʻano, ka momona keʻokeʻo a me ka momona ʻeleʻele. ʻO ka momona keʻokeʻo, ʻike ʻia hoʻi ʻo ka momona visceral, ua hana ʻia me nā kulu lipid a me kahi ʻāpana lahilahi i loko o kahi nucleus a me ka cytoplasm. Hoʻoulu nui ia a puni ko mākou ʻōpū; ʻoiai ʻo ka momona ʻeleʻele, ʻike ʻia hoʻi ʻo BAT i hoʻokomo ʻia, hana e hoʻoponopono i ka mahana o ke kino i ke anuanu.
Aia nā haʻawina kūpono e hōʻike ana i ka hoʻololi ʻana o 6-paradol i ka ʻiʻo adipose keʻokeʻo i loko o ka ʻiʻo adipose brown, no laila e hoʻonui ai i ka momona momona i mālama ʻia no ka ikehu. Eia kekahi, hoʻohana ka ʻiʻo adipose brown i ke kō koko a me nā lipids, no laila e hoʻomaikaʻi ai i ka metabolism glucose a me nā pae lipid. No laila, ʻoi aku ka nui o ka ʻiʻo adipose brown i loaʻa iā ʻoe, ʻoi aku ka nui o ka momona o ke kino e hoʻopau ʻia e like me ka ikehu, pēlā e hoʻonui ai i kāu hoʻolilo ikehu i kēlā me kēia lā.
Ka hopena
I ka hopena, ʻo 6-paradol kahi pūhui ikaika i loaʻa i ka ginger. Ua hōʻike ʻia he anti-inflammatory, anti-cancer, anti-obesity, antidiabetic, a me nā waiwai neuroprotective. Manaʻo ʻia he palekana ke ʻai. ʻO ke ala maikaʻi loa e loaʻa ai ka 6-paradol ʻo ka lawe ʻana i kahi mea hoʻohui. Eia naʻe, ma mua o ka lawe ʻana i kekahi mea hoʻohui, pono e kamaʻilio me kāu kauka.
Ka manawa hoʻouna: Jun-07-2023
