J-147 mea hana pauka CAS No.: 1146963-51-0 99.0% maemae min. no nā mea hoʻohui
Nā Kūlana Huahana
inoa huahana | 2,2,2-Trifluoroacetic acid 1-(2,4-DiMethylphenyl)-2-[(3-Methoxyphenyl)Methylene]hydrazide] |
inoa ʻē aʻe | J-147, J147 |
CAS No. | 1146963-51-0 |
ʻAno molekala | C18H17F3N2O2 |
Kaumaha molekula | 350.33 |
Maemae | 99% |
Ka nana aku | Pauda keʻokeʻo |
Hoʻopili | 1kg no ka ʻeke |
Palapala noi | nootropics |
Hoʻolauna Huahana
ʻO ka J-147 kahi neuroprotectant hoʻoikaika waha i loaʻa mua mai ka curcumin, ka mea hana i ka turmeric. ʻAʻole like me ka curcumin, ua hele maikaʻi ʻo ia i ka pale koko-lolo. Ma waena o lākou, hana ʻo J-147 ma ka hoʻopaʻa ʻana i ka ATP synthase. Hoʻopili ʻia ka overproduction o ATP me ke kaʻina hana ʻelemakule. Ma waho aʻe o ka hoʻonui ʻana i nā pae o nā neurotransmitters NGF a me BDNF, hiki iā J-147 ke hoʻomalu i kēia. Eia hou, J-147 inhibits monoamine oxidase B a me dopamine transporter. Hoʻoikaika i ka ulu ʻana o ka lolo ma o ka hoʻonui ʻana i nā pae o ka nerve growth factor (NGF) a me ka brain-derived neurotrophic factor (BDNF). ʻO ka mea nui loa, hiki iā J-147 ke hoʻoikaika i ka ulu ʻana o nā pūnaʻi nerve hou, hoʻonui i ka hiki ke aʻo a me ka hoʻomanaʻo o ka lolo, a hoʻomaikaʻi i ka hana cognitive.
Hiʻona
(1) Maʻemaʻe kiʻekiʻe: Hiki iā J-147 ke loaʻa nā huahana maʻemaʻe kiʻekiʻe ma o ka hoʻomaʻemaʻe ʻana i nā kaʻina hana. ʻO ka maʻemaʻe kiʻekiʻe, ʻoi aku ka maikaʻi o ka bioavailability a me ka liʻiliʻi o nā hopena ʻino.
(2) Palekana: Ua hōʻoia ʻia ʻo J-147 he palekana no ke kino kanaka.
(3) Paʻa: He kūpaʻa maikaʻi ko J-147 a hiki ke mālama i kāna hana a me ka hopena ma lalo o nā kaiapuni like ʻole a me nā kūlana mālama.
(4) Maʻalahi e komo: Hiki ke hoʻopili koke ʻia ʻo J-147 e ke kino o ke kanaka, komo i ke kahe koko ma o ka ʻōpū, a hāʻawi ʻia i nā ʻiʻo a me nā ʻāpana like ʻole.
Nā noi
ʻO J-147 kahi pūhui synthetic nona ka hana mua e pili ana i ka hoʻonui ʻana i ka mitochondrial, a laila e hoʻonui ai i ka hana ikehu ma ka pae kelepona. Hoʻolālā ʻia ʻo J-147 e hoʻonui i ka hiki o ka lolo e hoʻoponopono a pale iā ia iho mai ka pōʻino pili makahiki ma o ka hoʻomaikaʻi ʻana i ka hana mitochondrial. Hoʻohui ʻia, hōʻike ʻo J-147 i nā waiwai anti-inflammatory a me nā antioxidant, e hoʻonui hou i kona hopena neuroprotective. Hiki iā J-147 ke hoʻoikaika i ka ulu ʻana o nā pūnaʻi aʻalolo hou, hoʻonui i ka hiki ke aʻo a me ka hoʻomanaʻo o ka lolo, a hoʻomaikaʻi i ka hana cognitive.